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Table 1 Demographic data, IQ, the MCCB scores, and clinical information in patients and health controls

From: Relationships between abnormal neural activities and cognitive impairments in patients with drug-naive first-episode schizophrenia

 

dn-FES (n = 69)

HC (n = 74)

Statistics

p Value

Age (years, mean ± SD)

24.22 ± 7.08

26.27 ± 6.97

T = 1.75

0.083

Sex (male/female)

50/19

45/29

X2 = 1.48

0.142

Education (years, mean ± SD)

13.23 ± 2.81

14.69 ± 3.10

T = 2.94

0.004

DUP (mouths, mean ± SD)

13.74 ± 11.76

NA

NA

NA

Smokers/Nonsmorkers

6/63

0/74

X2 = 6.72

0.01

PANSS

 Positive symptoms

24.42 ± 3.88

NA

NA

NA

 Negative symptoms

17.58 ± 4.10

NA

NA

NA

 General

42.19 ± 3.55

NA

NA

NA

 All totals

84.19 ± 8.25

NA

NA

NA

Cognitive domains

 Speed of processing

35.42 ± 10.79

51.22 ± 8.46

F = 50.48

< 0.001

 Verbal learning

35.51 ± 11.07

46.35 ± 9.78

F = 19.62

< 0.001

 Working memory

34.22 ± 8.92

45.12 ± 7.10

F = 33.56

< 0.001

 Reasoning/problem solving

42.90 ± 11.56

53.53 ± 8.17

F = 20.24

< 0.001

 Visual learning

39.45 ± 11.91

50.55 ± 7.87

F = 23.17

< 0.001

 Attention/vigilance

35.04 ± 11.49

48.03 ± 7.22

F = 36.14

< 0.001

 Social cognition

32.68 ± 11.28

37.81 ± 9.34

F = 4.99

0.008

 overall composite

28.07 ± 12.27

45.97 ± 8.13

F = 55.01

< 0.001

 IQ

104.28 ± 11.81

115.55 ± 8.30

F = 50.48

< 0.001

  1. dn-FES, drug-naive First-Episode Schizophrenia; HC, Healthy Control; DUP, Duration of Untreated Psychosis; NA, Not Applicable. p < 0.05 represents a significant difference. The effect of smoking was controlled as a covariate to the analysis in cognitive domains