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Table 1 Demographic data, IQ, the MCCB scores, and clinical information in patients and health controls

From: Relationships between abnormal neural activities and cognitive impairments in patients with drug-naive first-episode schizophrenia

  dn-FES (n = 69) HC (n = 74) Statistics p Value
Age (years, mean ± SD) 24.22 ± 7.08 26.27 ± 6.97 T = 1.75 0.083
Sex (male/female) 50/19 45/29 X2 = 1.48 0.142
Education (years, mean ± SD) 13.23 ± 2.81 14.69 ± 3.10 T = 2.94 0.004
DUP (mouths, mean ± SD) 13.74 ± 11.76 NA NA NA
Smokers/Nonsmorkers 6/63 0/74 X2 = 6.72 0.01
PANSS
 Positive symptoms 24.42 ± 3.88 NA NA NA
 Negative symptoms 17.58 ± 4.10 NA NA NA
 General 42.19 ± 3.55 NA NA NA
 All totals 84.19 ± 8.25 NA NA NA
Cognitive domains
 Speed of processing 35.42 ± 10.79 51.22 ± 8.46 F = 50.48 < 0.001
 Verbal learning 35.51 ± 11.07 46.35 ± 9.78 F = 19.62 < 0.001
 Working memory 34.22 ± 8.92 45.12 ± 7.10 F = 33.56 < 0.001
 Reasoning/problem solving 42.90 ± 11.56 53.53 ± 8.17 F = 20.24 < 0.001
 Visual learning 39.45 ± 11.91 50.55 ± 7.87 F = 23.17 < 0.001
 Attention/vigilance 35.04 ± 11.49 48.03 ± 7.22 F = 36.14 < 0.001
 Social cognition 32.68 ± 11.28 37.81 ± 9.34 F = 4.99 0.008
 overall composite 28.07 ± 12.27 45.97 ± 8.13 F = 55.01 < 0.001
 IQ 104.28 ± 11.81 115.55 ± 8.30 F = 50.48 < 0.001
  1. dn-FES, drug-naive First-Episode Schizophrenia; HC, Healthy Control; DUP, Duration of Untreated Psychosis; NA, Not Applicable. p < 0.05 represents a significant difference. The effect of smoking was controlled as a covariate to the analysis in cognitive domains