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Table 2 Perceived Impacts of AP Side Effects on Social Functioning (N = 195)

From: Antipsychotic treatment experiences of people with bipolar I disorder: patient perspectives from an online survey

AP Side Effect Na Impacted Interactions with People (not including family) Impacted Relationships with Family Impacted Romantic Relationships Made You Feel Embarrassed in Front of Other People
Feeling drowsy or tired 165 75 (45.5%) 80 (48.5%) 64 (38.8%) 33 (20.0%)
Feeling a lack of emotion 157 69 (43.9%) 93 (59.2%) 75 (47.8%) 32 (20.4%)
Anxiety 156 104 (66.7%) 95 (60.9%) 77 (49.4%) 76 (48.7%)
Weight gain 150 42 (28.0%) 45 (30.0%) 59 (39.3%) 73 (48.7%)
Dry mouth 150 30 (20.0%) 31 (20.7%) 19 (12.7%) 31 (20.7%)
Restlessness 146 61 (41.8%) 48 (32.9%) 44 (30.1%) 36 (24.7%)
Trouble concentrating 141 72 (51.1%) 69 (48.9%) 52 (36.9%) 47 (33.3%)
Feeling like a “zombie” 137 58 (42.3%) 69 (50.4%) 48 (35.0%) 35 (25.5%)
Digestive (gastrointestinal) problems, including nausea 135 31 (23.0%) 34 (25.2%) 27 (20.0%) 40 (29.6%)
Sexual dysfunction (for example, loss of sex drive or performance issues) 133 12 (9.0%) 13 (9.8%) 84 (63.2%) 11 (8.3%)
Involuntary spasms, movements, twitching, or stiffness 123 34 (27.6%) 35 (28.5%) 24 (19.5%) 44 (35.8%)
Dizziness/fainting 123 27 (22.0%) 23 (18.7%) 21 (17.1%) 28 (22.8%)
  1. AP Antipsychotic
  2. a N only includes participants who experienced the listed AP medication side effect
  3. Percentages are calculated based on the N for each side effect
  4. Side effects are listed in order of descending overall proportion of participants who reported experiencing the side effect
  5. The three most frequently selected side effects for each of the four categories are bolded