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Table 2 Impact of PRIME mental health care plan on individual level outcomes

From: Impact of integrated district level mental health care on clinical and functioning outcomes of people with depression and alcohol use disorder in Nepal: a non-randomised controlled study

  Control group Treatment group Adjusted β (95%CI) P Effect size (95%CI)
N Mean (SD) Adjusted mean change (95%CI) from BL N Mean (SD) Adjusted mean change (95%CI) from BL
Depression Cohort
 PHQ-9
  Baseline 72 12.3 (2.15) 137 12.1 (4.13)  
  Midline 49 6.3 (5.06) −6.22 (−7.64 to −4.79) 110 4.7 (4.32) −7.09 (−8.17 to − 6.02) −0.88 (−2.66 to 0.91) 0.336 − 0.17 (− 0.50, 0.17)
  Endline 55 6.6 (4.94) −5.53 (− 6.91 to − 4.14) 111 4.8 (4.60) −6.93 (− 8.07 to − 5.78) −1.40 (−3.20 to 0.40) 0.127 −0.25 (− 0.57, 0.07)
 WHODAS
  Baseline 72 30.0 (15.55) 137 35.7 (18.55)  
  Midline 49 21.7 (18.50) −8.08 (− 13.62 to − 2.54) 110 18.9 (18.83) −14.70 (− 19.37 to − 10.03) −6.62 (− 13.86 to 0.63) 0.073 −0.31 (− 0.64, 0.03)
  Endline 55 22.8 (18.89) −6.71 (− 12.28 to − 1.13) 111 19.8 (20.92) − 13.90 (− 19.00 to − 8.81) − 7.20 (− 14.75 to 0.35) 0.062 − 0.31 (− 0.63, 0.02)
AUD Cohort
 AUDIT
  Baseline 57 16.4 (6.53) 175 25.4 (6.55)  
  Midline 28 16.0 (5.92) 1.66 (−0.83 to 4.15) 135 10.4 (9.87) −13.48 (− 15.94 to − 11.01) −15.13 (− 18.63 to − 11.63) < 0.001 −1.76 (− 2.17, − 1.35)
  Endline 35 16.9 (9.04) 1.09 (− 2.36 to 4.54) 142 15.7 (10.74) − 8.03 (− 10.59 to − 5.48) −9.12 (− 13.41 to − 4.83) < 0.001 − 0.79 (− 1.16, − 0.42)
 WHODAS
  Baseline 57 17.5 (15.11) 175 22.1 (17.90)  
  Midline 28 13.4 (12.58) − 2.57 (− 8.00 to 2.86) 135 12.3 (15.77) − 8.83 (− 12.75 to − 4.92) − 6.26 (− 12.95 to 0.43) 0.067 −0.38 (− 0.79, 0.03)
  Endline 35 15.5 (13.03) 1.23 (− 4.82 to 7.28) 142 13.6 (14.33) −8.03 (− 11.83 to − 4.23) − 9.26 (− 16.41 to − 2.12) 0.011 − 0.48 (− 0.85, − 0.11)
  1. AUDIT Alcohol use disorder identification test, BL Baseline, PHQ-9 Patient Health Questionnaire – 9 item, SD Standard deviation, WHODAS WHO Disability Assessment Schedule