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Table 2 Poisson regression: prevalence of and factors associated with major depressive disorder among people living with HIV/AIDS in Felege-Hiwot Referral Hospital (FHRH), Northwest Ethiopia, (N = 391)

From: Major depressive disorder and its association with adherence to antiretroviral therapy and quality of life: cross-sectional survey of people living with HIV/AIDS in Northwest Ethiopia

Sociodemographic and clinical factors

Prevalence of MDD, % (n)

Unadjusted Poisson regression

Adjusted Poisson regression

Risk ratio

95%CI

P value

Risk ratio

95%CI

P value

Age in years a

18–29

31.4 (16)

1.11

0.56, 2.19

0.770

   

30–39

33.5 (54)

1.18

0.69, 2.04

0.544

   

40–49

33.6 (40)

1.19

0.67, 2.09

0.555

   

50+

29.6 (16)

Reference

Reference

    

Gender

Male

25.2 (30)

Reference

Reference

    

Female

36.1 (97)

1.47

0.97, 2.21

0.067

1.13

0.72, 1.78

0.600

Marital status

Married/in relationship

25.7 (48)

Reference

Reference

 

Reference

Reference

 

Single

37.7 (20)

1.47

0.87, 2.48

0.148

1.13

0.65, 1.96

0.675

Divorced/widowed

39.1 (59)

1.52

1.04, 2.23

0.031

1.01

0.67, 1.53

0.968

Educational status

Illiterate

46.3 (57)

2.11

1.11, 4.02

0.024

1.04

0.43, 2.50

0.930

Primary education

28.0 (35)

1.27

0.65, 2.51

0.485

0.90

0.39, 2.10

0.812

Secondary education

25.8 (24)

1.17

0.58, 2.40

0.661

0.83

0.35, 1.99

0.682

Tertiary education

22.0 (11)

Reference

Reference

 

Reference

  

Employment

Public employed

17.9 (15)

Reference

Reference

 

Reference

  

Self employed

30.8 (56)

1.64

0.94, 2.85

0.083

1.40

0.68, 2.89

0.366

Unemployed

44.4 (55)

2.36

1.35, 4.11

< 0.003

1.75

0.84, 3.63

0.135

Perceived social support

High support

24.3 (55)

Reference

Reference

 

Reference

Reference

 

Moderate support

41.9 (54)

1.70

1.17, 2.46

< 0.005

1.21

0.82, 1.78

0.337

Low support

55.6 (15)

2.25

1.28, 3.97

< 0.005

1.25

0.67, 2.31

0.481

ART regimen

First-line

27.8 (80)

Reference

Reference

 

Reference

Reference

 

Second-line

45.9 (45)

1.64

1.14, 2.36

< 0.008

1.31

0.90, 1.91

0.157

Functional disability

No

11.0 (26)

Reference

Reference

 

Reference

Reference

 

Yes

65.4 (100)

5.76

3.77, 8.81

< 0.001

5.07

3.27, 7.86

< 0.001

Current CD4 count (last 6 months) a

< 200

35.7 (10)

0.98

0.51, 1.91

0.969

   

200–349

26.1 (18)

0.72

0.43, 1.21

0.215

   

350–499

28.4 (27)

0.78

0.51, 1.22

0.285

   

> 500

36.5 (65)

Reference

Reference

    

ART treatment duration in years a

1–5

29.2 (21)

0.81

0.49, 1.32

0.387

   

6–10

29.1 (39)

0.80

0.54, 1.19

0.278

   

11 and above

36.4 (63)

Reference

Reference

    
  1. NOTE: First-line regimen is the use of first choice antiviral drugs and a switch to second-line regimen is recommended when there is treatment failure with first-line treatments. ART: antiretroviral therapy. a variables not included in multivariate Poisson regression
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BMC Psychiatry

ISSN: 1471-244X

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