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Table 2 Poisson regression: prevalence of and factors associated with major depressive disorder among people living with HIV/AIDS in Felege-Hiwot Referral Hospital (FHRH), Northwest Ethiopia, (N = 391)

From: Major depressive disorder and its association with adherence to antiretroviral therapy and quality of life: cross-sectional survey of people living with HIV/AIDS in Northwest Ethiopia

Sociodemographic and clinical factors Prevalence of MDD, % (n) Unadjusted Poisson regression Adjusted Poisson regression
Risk ratio 95%CI P value Risk ratio 95%CI P value
Age in years a 18–29 31.4 (16) 1.11 0.56, 2.19 0.770    
30–39 33.5 (54) 1.18 0.69, 2.04 0.544    
40–49 33.6 (40) 1.19 0.67, 2.09 0.555    
50+ 29.6 (16) Reference Reference     
Gender Male 25.2 (30) Reference Reference     
Female 36.1 (97) 1.47 0.97, 2.21 0.067 1.13 0.72, 1.78 0.600
Marital status Married/in relationship 25.7 (48) Reference Reference   Reference Reference  
Single 37.7 (20) 1.47 0.87, 2.48 0.148 1.13 0.65, 1.96 0.675
Divorced/widowed 39.1 (59) 1.52 1.04, 2.23 0.031 1.01 0.67, 1.53 0.968
Educational status Illiterate 46.3 (57) 2.11 1.11, 4.02 0.024 1.04 0.43, 2.50 0.930
Primary education 28.0 (35) 1.27 0.65, 2.51 0.485 0.90 0.39, 2.10 0.812
Secondary education 25.8 (24) 1.17 0.58, 2.40 0.661 0.83 0.35, 1.99 0.682
Tertiary education 22.0 (11) Reference Reference   Reference   
Employment Public employed 17.9 (15) Reference Reference   Reference   
Self employed 30.8 (56) 1.64 0.94, 2.85 0.083 1.40 0.68, 2.89 0.366
Unemployed 44.4 (55) 2.36 1.35, 4.11 < 0.003 1.75 0.84, 3.63 0.135
Perceived social support High support 24.3 (55) Reference Reference   Reference Reference  
Moderate support 41.9 (54) 1.70 1.17, 2.46 < 0.005 1.21 0.82, 1.78 0.337
Low support 55.6 (15) 2.25 1.28, 3.97 < 0.005 1.25 0.67, 2.31 0.481
ART regimen First-line 27.8 (80) Reference Reference   Reference Reference  
Second-line 45.9 (45) 1.64 1.14, 2.36 < 0.008 1.31 0.90, 1.91 0.157
Functional disability No 11.0 (26) Reference Reference   Reference Reference  
Yes 65.4 (100) 5.76 3.77, 8.81 < 0.001 5.07 3.27, 7.86 < 0.001
Current CD4 count (last 6 months) a < 200 35.7 (10) 0.98 0.51, 1.91 0.969    
200–349 26.1 (18) 0.72 0.43, 1.21 0.215    
350–499 28.4 (27) 0.78 0.51, 1.22 0.285    
> 500 36.5 (65) Reference Reference     
ART treatment duration in years a 1–5 29.2 (21) 0.81 0.49, 1.32 0.387    
6–10 29.1 (39) 0.80 0.54, 1.19 0.278    
11 and above 36.4 (63) Reference Reference     
  1. NOTE: First-line regimen is the use of first choice antiviral drugs and a switch to second-line regimen is recommended when there is treatment failure with first-line treatments. ART: antiretroviral therapy. a variables not included in multivariate Poisson regression