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Table 5 Linear regression: association of socio-demographic and clinical factors with the domains of quality of life among people living with HIV/AIDS in Felege-Hiwot Referral Hospital, Northwest, Ethiopia, (N = 391)

From: Major depressive disorder and its association with adherence to antiretroviral therapy and quality of life: cross-sectional survey of people living with HIV/AIDS in Northwest Ethiopia

Sociodemographic and clinical factors

Physical

β (95%CI)

Psychological

β (95%CI)

Independence

β (95%CI)

Social

β (95%CI)

Environmental

β (95%CI)

Spiritual

β (95%CI)

Age

18–29

Reference

Reference

Reference

Reference

Reference

Reference

30–39

−0.05 (− 0.22, 0.11)

0.07 (− 0.09, 0.23)

− 0.01 (− 0.16, 0.15)

0.12 (− 0.03, 0.28)

0.18 (0.01, 0.37)

0.07 (− 0.07, 0.20)

40–49

− 0.10 (− 0.27, 0.08)

0.10 (− 0.07, 0.27)

−0.03 (− 0.20, 0.14)

0.10 (0.07, 0.27)

0.26 (0.06, 0.46)

0.08 (− 0.06, 0.23)

50+

−0.11 (− 0.32, 0.09)

0.16 (− 0.05, 0.36)

− 0.09 (− 0.30, 0.09)

0.14 (− 0.05, 0.33)

0.23 (0.02, 0.46)

0.11 (− 0.05, 0.28)

Marital status

Married/relationship

Reference

Reference

Reference

Reference

Reference

Reference

Single

−0.10 (− 0.27, 0.07)

0.01 (− 0.16, 0.17)

− 0.09 (− 0.25, 0.07)

−0.16 (− 0.32, 0.01)

0.18 (− 0.02, 0.37)

− 0.09 (− 0.23, 0.05)

Divorced/ widowed

0.01 (− 0.10, 0.13)

0.07 (− 0.04, 0.18)

0.06 (− 0.05, 0.17)

−0.08 (− 0.19, 0.03)

0.07 (− 0.07, 0.20)

−0.05 (− 0.14, 0.05)

Educational status

Illiterate

Reference

Reference

Reference

Reference

Reference

Reference

Primary education

0.20 (0.07, 0.33)

0.17 (0.04, 0.30)

0.22 (0.09, 0.35)

0.11 (− 0.01, 0.24)

0.12 (− 0.03, 0.28)

0.12 (0.01, 0.22)

Secondary education

0.21 (0.06, 0.35)

0.22 (0.07, 0.36)

0.21 (0.07, 0.35)

0.13 (−0.01, 0.27)

0.31 (0.14, 0.48)

0.13 (0.01, 0.25)

Tertiary education

0.27 (0.06, 0.48)

0.51 (0.30, 0.72)

0.35 (0.15, 0.56)

0.16 (−0.04, 0.37)

0.33 (0.10, 0.57)

0.23 (0.06, 0.41)

Employment status

Public servant

−0.08 (− 0.26, 0.09)

−0.09 (− 0.26, 0.09)

0.01 (− 0.16, 0.18)

−0.01 (− 0.17, 0.16)

−0.04 (− 0.23, 0.16)

−0.09 (− 0.23, 0.06)

Self employed

−0.04 (− 0.16, 0.08)

0.17 (0.05, 0.29)

0.07 (− 0.04, 0.19)

−0.11 (− 0.22, 0.01)

−0.01 (− 0.14, 0.13)

−0.07 (− 0.17, 0.02)

Unemployed

Reference

Reference

Reference

Reference

Reference

Reference

Perceived social support

Low support

Reference

Reference

Reference

Reference

Reference

Reference

Moderate support

0.15 (−0.05, 0.34)

0.34 (0.15, 0.53)

0.23 (0.05, 0.42)

0.10 (− 0.08, 0.29)

0.11 (−0.13, 0.34)

0.19 (0.03, 0.35)

High support

0.25 (0.06, 0.44)

0.60 (0.42, 0.79)

0.37 (0.19, 0.56)

0.68 (0.50, 0.87)

0.45 (0.22, 0.68)

0.28 (0.13, 0.44)

ART regimen

First-line

0.15 (0.04, 0.27)

0.19 (0.07, 0.30)

0.11 (0.01, 0.23)

0.10 (−0.01, 0.21)

0.08 (−0.05, 0.22)

0.08 (− 0.02, 0.17)

Second-line

Reference

Reference

Reference

Reference

Reference

Reference

Functional Disability

No

0.39 (0.28, 0.49)

0.55 (0.44, 0.66)

0.35 (0.25, 0.45)

0.25 (0.15, 0.35)

0.10 (−0.02, 0.22)

0.17 (0.08, 0.26)

Yes

Reference

Reference

Reference

Reference

Reference

Reference

Current CD4 count (last 6 months)

< 200

Reference

Reference

Reference

Reference

Reference

Reference

200–349

−0.07 (−0.27, 0.12)

0.07 (−0.12, 0.26)

− 0.03 (− 0.21, 0.16)

0.04 (− 0.14, 0.22)

−0.08 (− 0.30, 0.15)

0.14 (− 0.02, 0.30)

350–499

0.03 (− 0.16, 0.21)

0.08 (− 0.10, 0.26)

0.07 (− 0.10, 0.25)

0.04 (− 0.14, 0.21)

−0.03 (− 0.24, 0.18)

0.13 (− 0.02, 0.28)

> 500

0.01 (− 0.17, 0.17)

0.01 (− 0.15, 0.18)

−0.04 (− 0.20, 0.12)

0.03 (− 0.13, 0.19)

−0.05 (− 0.24, 0.15)

0.05 (− 0.09, 0.19)

ART treatment duration in years

1–5

Reference

Reference

Reference

Reference

Reference

Reference

6–10

0.17 (0.03, 0.32)

0.12 (−0.02, 0.27)

0.13 (−0.01, 0.27)

0.05 (− 0.09, 0.19)

0.01 (− 0.15, 0.18)

0.17 (0.05, 0.29)

11+

0.03 (−0.11, 0.18)

0.03 (−0.12, 0.17)

− 0.05 (− 0.19, 0.09)

−0.04 (− 0.09, 0.19)

−0.14 (− 0.30, 0.03)

0.04 (− 0.08, 0.16)

  1. The results in this table were identified in multivariate linear regression. All variables associated with overall QoL at > 0.2 were controlled multivariate analyses with each domain of QoL. First-line regimen is the use of first choice antiviral drugs and a switch to second-line regimen is recommended when there is treatment failure with first-line treatments. ART antiretroviral therapy