Effects and feasibility of hyperthermic baths in comparison to exercise as add-on treatment to usual care in depression: a randomised, controlled pilot study

Table 3 Between-group differences in the intent-to-treat last observation carried forward sample

Outcome Measure	HTB Group (N = 22)	PEP Group (N = 23)	HTB vs PEP Adjusted mean difference^c (95% CI)	p^c
HAM-D total score
Baseline	21.2 (3.3)	22.2 (3.1)
T1: 2 weeks^a	15.8 (4.4)	20.8 (4.2)	4.3 (2.16 to 6.42)	< 0.001
T2: 8 weeks^b	15.3 (5.8)	19.0 (6.1)	2.9 (−0.40 to 6.14)	0.084
BDI-II
Baseline	29.0 (5.8)	31.1 (8.1)
T1: 2 weeks^b	20.3 (8)	29.1 (8.8)	7.5 (2.99 to 11.93)	0.002
T2: 8 weeks^b	20.5 (10.8)	24.8 (11.8)	3.1 (−3.36 to 9.53)	0.340
PSQI
Baseline	10.2 (3.8)	11.4 (3.7)
T1: 2 weeks^b	8.7 (3.7)	11.5 (4.1)	2.0 (0.14 to 3.92)	0.036
T2: 8 weeks^b	8.3 (3.2)	10.7 (4.1)	1.8 (−0.13 to 3.64)	0.067

Abbreviations: HAM-D 17-Item Hamilton Depression Rating Scale, BDI-II Becks Depression Inventar II, PSQI The Pittsburgh Sleep Quality Index
Data are shown as mean and standard deviation (SD).
^aPrimary outcome
^bPrespecified secondary outcome
^cLinear regression analyses adjusted for baseline scores

ISSN: 1471-244X