Table 2 Domains of social cognition in individuals with 22q11DS linked to psychopathology and social outcomes
Author (year) | N | Age M (SD), (range) | IQ (SD), (range) | Social Cognition | Social Cognition – Psychopathology | Social Cognition - Social Outcomes | ||||
|---|---|---|---|---|---|---|---|---|---|---|
Task | Instrument | Measure | Association | Instrument | Measure | Association | ||||
| Â | Â | Â | Â | EP | Â | Â | Â | Â | Â | Â |
Schneider et al. (2017) [56] | 35 | 18.06 (3.40), (11–24) | (−) | BFRT BFRT | SPQ SPQ | paranoid schiz.symptoms negative schiz.symptoms | r = −  0.362, p = 0.022 r = −0.321, p = 0.060 | DAS | severity of negative performance beliefs | r = −0.388, p = 0.021 |
Zaharia et al. (2018) [58] | 75 | T1 12.81 (3.57),(−) | 71.96 (11.25),(−) | Face Discrimination Task:correct answers on CD trials | PANSS | negative symptoms | r = −0.293, p = 0.02 | PANSS negative | used as measure of social abilities | r = − 0.293, p = 0.02 |
| Â | Â | Â | Â | Face Discrimination Task | A-CBCL | internalizing, anxious/depressive symptoms | 0 | Â | Â | Â |
Vangkilde et al. (2016) [49] | 29 | 15.7 (2.8), (−) | 79.52 (−), (35–113) | ERT ERT | SIPS | negative prod.symptoms | d.r. | ABAS Social (p/s.r.) SRS Total (p.r.) | social functioning social skills | 0 0 |
Badoud et al. (2017) [55] | 28 | 17.79 (2.89), (11–21) | 75.33 (11.66),(−) | Pictures of Facial Affect | SPQ | schizitypal traits | 0 | VABS (p.r.) | communication, daily living skills, socialization | 0 |
Weinberger et al. (2018) [59] | 44 | 20.7 (6.0), (12–33) | 77.2 (11.0),(−) | Social Cognition Total: (Emotion Ident., Differention Age Differentiation) | SIPS SOPS | negative symptoms negative prod. symptoms (total negative score) | 0 0 | VABS (p.r.) | communication, daily living skills, socialization | n.r. |
Campbell et al. (2011) [50] | 50 | 10.99 (2.9), (6–17) | 65.8 (9.3), (40–94) | Face Process Skills Battery | SDQ | emotional problems | n.r. | SDQ (p.r.) | peer relationship problems | r = 0.33, p < 0.03 |
Campbell et al. (2015) [54] | 24 | 16.75 (3.14), (12–21) | 75.9 (14.9), (56–115) | EAT | SDQ | emotional problems | n.r. | SDQ (p.r.) | peer relationship problems | beta = 0.69, p < 0.05 |
Dubourg et al. (2018) [57] | 22 | 20.3 (5.2), (12–32) | 74 (12),(−) | BFRT BFRT BFRT BFRT | DICA, SCID-I K-SADS-PL SIPS SIPS | psychiatric disorders psychiatric disorders positive prod. symptoms negative prod. symptoms | n.r. n.r. n.r. n.r. | SRS (p.r.) | social skills | 0 |
Shashi et al. (2012) [53] | 66 | 10.5 (2.6), (−) | (−) | DANVA | CBCL, C-DISC | psychiatric disorders | n.r. | SSRS Total (p.r.) | social skills | 0 |
| Â | Â | Â | Â | ToM | Â | Â | Â | Â | Â | Â |
Vangkilde et al. (2016) [49] | 29 | 15.7 (2.8), (−) | 79.52 (−), (35–113) | TASIT Total TASIT Total | SIPS | negative prod. symptoms positive prod. symptoms | d.r. 0 | ABAS Social (p./s.r) SRS Total (p.r.) | social functioning social skills | 0 0 |
Badoud et al. (2017) [55] | 28 | 17.79 (2.89), (11–21) | 75.33 (11.66), (−) | The Director Task The Director Task | SPQ SPQ | negative schiz. traits disorganised schiz. traits | RT, r = 0.425, p = 0.062 RT, r = 0.393, p = 0.087 | VABS (p.r.) | communication, daily living skills, socialization | 0 |
(without participants on antipsychotic medication) | The Director Task The Director Task The Director Task | SPQ SPQ SPQ | positive schiz. traits negative schiz. traits disorganised schiz. traits | r = 0.464, p = 0.046 r = 0.598, p = 0.007 r = 0.576, p = 0.010 |  |  |  | |||
Ho et al. (2012) [52](SUNY) (UCLA) | 63 | Â | Â | The Animations Task: | Â | Â | Â | Â | Â | Â |
34 29 | 17.1 (1.9), (14–22) 13.7 (5.5), (6–25) | 74.5 (13.2), (−) 80.5 (13.7), (−) | Intentionality Appropriatedness | SIPS SIPS | negative prod. symptoms positive prod. symptoms | 0 0 | SRS (p.r.) SRS (p.r.) | social skills social skills | r = −0.283, p < 0.05 r = −0.314, p < 0.05 | |
Campbell et al. (2011) [50] | 50 | 10.99 (2.9), (6–17) | 65.8 (9.3), (40–94) | false-belief stories | SDQ | emotional problems | n.r. | SDQ (p.r.) | peer relationship problems | r = 0.3, p < 0.03 |
Campbell et al. (2015) [54] | 24 | 16.75 (3.14), (12–21) | 75.9 (14.9), (56–115) | PST (false-belief stories) | SDQ | emotional problems | n.r. | SDQ (p.r.) | peer relationship problems | 0 |