Table 4 Comparisons between 195 T1DM patients with low and 83 T1DM patients with high levels of sTWEAK
| Â | sTWEAK | ||
|---|---|---|---|
|  | Low levels (< 7.2 ng/ml) | High levels (≥7.2 ng/ml) | P - value a |
N | 195 | 83 | Â |
Age (years) | 42 (32, 51) | 42 (29, 51) | 0.79 |
Diabetes duration (years) | 20 (11, 30) | 18 (9, 29) | 0.58 |
Sex | |||
 Women | 89 (46) | 30 (36) | 0.15 b |
 Men | 106 (54) | 53 (64) | |
Depression | 27 (14) | 2 (2) | 0.003 b |
High galectin-3 (≥2.6 ng/ml) c | 27 (14) | 14 (17) | 0.58 b |
High HbA1c (> 70 mmol/mol (> 8.6%)) | 53 (27) | 22 (26) | > 0.99 b |
Total cholesterol (mmol/l) | 4.6 (4.1, 5.2) | 4.5 (4.0, 5.0) | 0.13 |
LDL (mmol/l) | 2.9 (2.4, 3.4) | 2.8 (2.4, 3.2) | 0.34 |
Triglycerides (mmol/l) | 0.9 (0.7, 1.3) | 0.8 (0.7, 1.2) | 0.19 |
HDL (mmol/l) | 1.5 (1.3, 1.8) | 1.6 (1.3, 1.8) | 0.71 |
Triglycerides/HDL-cholesterol ratio | 0.6 (0.4–0.9) | 0.6 (0.4–0.8) | 0.23 |
S-Creatinine (μmol/l) d | 70 (62, 77) | 70 (62, 80) | 0.44 |
Abdominal obesity e | 33 (17) | 11 (13) | 0.48 b |
BMI (kg/m2) f | 24.6 (22.4, 27.9) | 24.6 (23.1, 26.1) | 0.92 |
Systolic BP (mm Hg) | 120 (110, 130) | 120 (110, 130) | 0.34 |
Diastolic BP (mm Hg) | 70 (70, 75) | 70 (65, 78) | 0.54 |
Hypoglycemia (severe episodes) | 7 (4) | 4 (5) | 0.74 b |
Smoking g | 20 (11) | 8 (10) | > 0.99 b |
Physical inactivity h | 24 (13) | 5 (6) | 0.19 b |
Continuous subcutaneous insulin infusion | 11 (6) | 14 (17) | 0.005 b |
Antidepressants | 16 (8) | 6 (7) | > 0.99 b |
Lipid lowering drugs | 92 (47) | 36 (43) | 0.60 b |
Antihypertensive drugs | 62 (32) | 26 (31) | > 0.99 b |
Cardiovascular complications | 8 (4) | 2 (2) | 0.73 b |