The relationship between dietary patterns and depression mediated by serum levels of Folate and vitamin B12

BMC Psychiatry

Table 3 The comparison of the serum biochemical markers between case and control groups

Biochemical factors	Case (Mean ± SE)	Control (Mean ± SE)	P_value^a	P _value^b	OR(95%CI)
Folate (ng/ml)	5.8 ± 0.3	7.7 ± 0.28	<0.001	<0.001	0.54 (0.38–0.75)
Vitamin B12(pg/ml)	550.9 ± 55.1	954.9 ± 57.7	<0.001	<0.001	0.996 (0.993–0.998)
Hcy¹ (μmol/l)	11.2 ± 1.1	11.9 ± 0.9	0.2	0.5	0.97 (0.9–1.05)
Trp²(μmol/l)	70.3 ± 2.9	75.3 ± 3.9	0.3	0.1	0.97 (0.94–1.01)
Tryptophan/competing amino acids³	0.113 ± 0.003	0.104 ± 0.002	0.02	0.5	1.46 (0.45–4.76)

^a T- test for Square, square root or logarithm
^b Multiple logistic regression after adjusting for job, education, marital status, children number, smoking and hookah use, depression history, unemployment history in the past 5 year, tragic events in the past 6 months and the whole lifetime, energy intake, physical activity and dietary patterns
¹ Homocystein
² Tryptophan
³ Valine, leucine, tyrosine, phenylalanine and isoleucine (These amino acids compete for the same cerebral uptake mechanism)

ISSN: 1471-244X