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Table 1 Demographic and clinical characteristics of the study participants at inclusion

From: Lower serum nicotinamide N-methyltransferase levels in patients with bipolar disorder during acute episodes compared to healthy controls: a cross-sectional study

 

Healthy controls (n = 65)

BD patients (n = 80)

p†

Age (years)

34 (25, 46)

31 (24, 45)

–

Sex (M/F)

34/31

49/31

–

Metabolic parameters

 BMI (kg/m2)

23.03 (21.76, 24.53)

23.98 (22.29,

26.79)

0.064

 SBP (mmHg)

120 (112, 135)

126 (120, 142)

0.031*

 DBP (mmHg)

80 (70, 85)

85 (71, 88)

0.049*

 TG (mmol/L)

1.03 (0.71, 1.76)

1.42 (0.92, 1.83)

0.105

 CHO (mmol/L)

4.31 (3.83, 5.42)

4.70 (4.33, 5.53)

0.026*

 HDL-c (mmol/L)

1.24 (1.05, 1.47)

1.29 (1.09, 1.48)

0.618

 LDL-c (mmol/L)

3.05 (2.62, 3.65)

3.14 (2.85, 3.64)

0.24

 apo A(g/L)

1.37 (1.23, 1.49)

1.51 (1.35, 1.58)

0.004**

 apo B(g/L)

0.92 (0.77, 1.12)

0.88 (0.75, 1.02)

0.529

 FBG (mmol/L)

5.06 (4.47, 5.34)

4.89 (4.49, 5.67)

0.808

Comorbidities

 Obesity, n (%)

6 (9.2%)

13 (16.3%)

0.159

 Dyslipidemia, n (%)

25 (38.5%)

30 (37.5%)

0.316

 IGM, n (%)

5 (7.7%)

6 (7.6%)

0.603

Medications

 SGA+ MS, n (%)

–

23 (28.8%)

–

 SGA+ AED, n (%)

–

22 (27.5%)

–

 SGA+ MS+ AED, n (%)

–

12 (15%)

–

 Drug-naive, n (%)

–

23 (28.8%)

–

  1. Data are presented as mean ± SD, median (interquartile range), or n (%). †p-values of Mann-Whitney U test, Student’s unpaired t test or χ2
  2. ∗p < 0.05, ∗∗p < 0.01