Table 2 Competing risk regression analyses results for EEAA, IEAA, AgeAccelPheno and AgeAccelGrim
| Â | Hazard Ratios (95% Confidence Interval) for Probable Dementia | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Results for EEAA | Results for IEAA | Results for AgeAccelPheno | Results for AgeAccelGrim | |||||||||
Model 2 (n = 383) | Model 3 (n = 382) | Model 4 (n = 371) | Model 2 (n = 383) | Model 3 (n = 382) | Model 4 (n = 371) | Model 2 (n = 383) | Model 3 (n = 382) | Model 4 (n = 371) | Model 2 (n = 383) | Model 3 (n = 382) | Model 4 (n = 371) | |
Measure of age acceleration | 0.96 (0.92, 1.00) | 0.98 (0.95, 1.01) | 0.98 (0.95, 1.01) | 0.97 (0.92, 1.02) | 0.98 (0.95, 1.01) | 0.98 (0.95, 1.01) | 0.96 (0.93, 1.00) | 0.99 (0.96, 1.02) | 0.99 (0.96, 1.03) | 0.89 (0.81, 0.97) | 0.95 (0.89, 1.01) | 0.95 (0.89, 1.01) |
Sex (female) | 0.92 (0.58, 1.44) | 0.87 (0.55, 1.40) | 0.87 (0.53, 1.41) | 1.02 (0.66, 1.59) | 0.93 (0.60, 1.44) | 0.94 (0.56, 1.47) | 1.06 (0.68, 1.63) | 0.97 (0.63, 1.49) | 0.97 (0.62, 1.52) | 0.84 (0.53, 1.34) | 0.83 (0.51, 1.36) | 0.84 (0.51, 1.38) |
APOE ɛ4 (non-carrier) | 0.43 (0.28, 0.65) | 0.42 (0.28, 0.64) | 0.40 (0.26, 0.60) | 0.43 (0.28, 0.67) | 0.43 (0.28, 0.65) | 0.40 (0.26, 0.61) | 0.43 (0.28, 0.67) | 0.43 (0.28, 0.65) | 0.40 (0.26, 0.61) | 0.45 (0.30, 0.69) | 0.44 (0.29, 0.67) | 0.41 (0.27, 0.64) |
Age acceleration by Sex interaction term | 1.03 (0.97, 1.09) | – | – | 1.01 (0.95, 1.08) | – | – | 1.04 (0.98, 1.10) | – | – | 1.05 (0.94, 1.18) | – | – |
Smoker (never) | – | 2.00 (1.30, 3.07) | 1.97 (1.27, 3.06) | – | 2.01 (1.31, 3.09) | 1.98 (1.28, 3.07) | – | 2.02 (1.30, 3.14) | 2.00 (1.27, 3.17) | – | 1.69 (1.06, 2.71) | 1.69 (1.05, 2.73) |
History of hypertension | – | – | 0.73 (0.47, 1.15) | – | – | 0.75 (0.48, 1.17) | – | – | 0.74 (0.47, 1.16) | – | – | 0.71 (0.45, 1.12) |
History of diabetes | – | – | 1.24 (0.44, 3.44) | – | – | 1.23 (0.45, 3.40) | – | – | 1.22 (0.44, 3.42) | – | – | 1.20 (0.44, 3.30) |
History of cardiovascular or cerebrovascular disease | – | – | 0.75 (0.44, 1.28) | – | – | 0.74 (0.44, 1.27) | – | – | 0.74 (0.44, 1.27) | – | – | 0.75 (0.44, 1.27) |