Decision-making about antidepressant medication use in pregnancy: a comparison between women making the decision in the preconception period versus in pregnancy

Table 3 Multivariable model for the relation between pregnancy status and intent to use antidepressants. Crude and adjusted models using odds ratios (OR) and 95% confidence intervals (CI)

Main Exposure Variable	Odds Ratio (95% CI)
Crude model^a
Preconception (vs. pregnant)	3.11 (1.33–7.32)
Adjusted model^b
Preconception (vs. pregnant)	2.79 (0.81–9.62)
Married/co-habitating (vs. single, divorced, widowed)	6.10 (0.58–64.7)
Current antidepressant use (vs. no current use)	12.4 (2.72–56.4)
Family physician involved in mental health care (vs. not)	1.32 (0.46–3.80)
Edinburgh Postnatal Depression Scale Score (Mean)	0.94 (0.82–1.07)
State-Trait Anxiety Inventory (State) ≥ 40 (vs. < 40)	0.62 (0.18–2.17)
Decisional Conflict Scale Score ≥ 37.5 (vs. < 37.5)	0.16 (0.04–0.67)

^a Nagelkerke R-squared 9.6%
^b Hosmer-Lemeshow Chi-Square = 3.83 (df 8), p = 0.872, Nagelkerke R-squared 44.6%

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