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Table 3 Results of logistic regression analyses explaining ANT-adherence in the total sample, clozapine and non-clozapine groups

From: Daily functioning and symptom factors contributing to attitudes toward antipsychotic treatment and treatment adherence in outpatients with schizophrenia spectrum disorders

  Model e Model f Model h Model g
Total sample OR OR OR OR
Age 1.01 1.02 1.02 1.01
Sex 2.17 1.99 1.63 2.14
Chlorpromazine equivalent 1.00 1.00 1.00 1.00*
ANT-attitude 1.04** 1.04** 1.03* 1.03*
ANT-insight 1.00 1.00 1.00 1.01
ANT-adverse effects 1.02 1.02 1.01 1.01
BPRS_total 0.97    
BPRS_positive symptoms   0.95   
HONOS_total    0.96  
HONOS_behaviour     1.24
HONOS_impairment     0.94
HONOS_symptoms     0.75
HONOS_social     1.20
ADL 0.73 0.73 0.77 0.74
IADL 1.19 1.22 1.2 1.25
social functioning 0.82 0.84 0.80 0.80
Nagelkerke R square 0.22 0.23 0.21 0.25
p for the model < 0.001 < 0.001 < 0.001 < 0.001
Non-clozapine group
 Age 1.03 1.04 1.04 1.04
 Sex 1.67 1.46 1.15 1.64
 Chlorpromazine equivalent 1.00 1.00 1.00 1.00
 ANT-attitude 1.05** 1.05** 1.04* 1.04*
 ANT-insight 1.00 1.00 0.99 1.00
 ANT-adverse effects 1.02 1.02 1.01 1.01
 BPRS_total 0.98    
 BPRS_positive symptoms   0.98   
 HONOS_total    1.03  
 HONOS_behaviour     1.45
 HONOS_impairment     1.06
 HONOS_symptoms     0.79
 HONOS_social     1.34
 ADL 0.76 0.73 0.79 0.74
 IADL 1.07 1.16 1.11 1.11
 social functioning 0.85 0.85 0.79 0.84
 Nagelkerke R square 0.29 0.30 0.26 0.33
p for the model < 0.01 < 0.001 < 0.01 < 0.01
Clozapine group
Age 0.99 1.00 0.99 0.93
Sex 3.82 4.23 4.23 19.31
Chlorpromazine equivalent 1.00 1.00 1.00 1.00
ANT-attitude 1.04 1.04 1.05 1.02
ANT-insight 1.00 1.00 0.98 1.00
ANT-adverse effects 1.02 1.03 1.02 1.07
BPRS_total 0.99    
BPRS_positive symptoms   0.96   
HONOS_total    0.93  
HONOS_behaviour     14.71
HONOS_impairment     0.39
HONOS_symptoms     0.78
HONOS_social     1.11
ADL 2.50 2.66 1.92 2.82
IADL 1.58 1.50 1.55 2.37*
social functioning 0.78 0.84 0.79 0.71
Nagelkerke R square 0.24 0.25 0.30 0.38
p for the model 0.31 0.28 0.21 0.15
  1. * p < 0.05 ** p < 0.01 ***p < 0.001
  2. In the presentation of categorical variables: a positive estimate indicates a better adherence for women. A positive estimate indicates a better adherence related to higher score in ANT-scales. High score in ANT -attitude, −insight and -side effect indicates positive attitudes toward medication, better sickness awareness and less experienced side effects. All models adjusted by age, gender, daily antipsychotic dose, ANT-insight, ANT-attitude and ANT-adverse effects