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Table 3 Results of logistic regression analyses explaining ANT-adherence in the total sample, clozapine and non-clozapine groups

From: Daily functioning and symptom factors contributing to attitudes toward antipsychotic treatment and treatment adherence in outpatients with schizophrenia spectrum disorders

 

Model e

Model f

Model h

Model g

Total sample

OR

OR

OR

OR

Age

1.01

1.02

1.02

1.01

Sex

2.17

1.99

1.63

2.14

Chlorpromazine equivalent

1.00

1.00

1.00

1.00*

ANT-attitude

1.04**

1.04**

1.03*

1.03*

ANT-insight

1.00

1.00

1.00

1.01

ANT-adverse effects

1.02

1.02

1.01

1.01

BPRS_total

0.97

   

BPRS_positive symptoms

 

0.95

  

HONOS_total

  

0.96

 

HONOS_behaviour

   

1.24

HONOS_impairment

   

0.94

HONOS_symptoms

   

0.75

HONOS_social

   

1.20

ADL

0.73

0.73

0.77

0.74

IADL

1.19

1.22

1.2

1.25

social functioning

0.82

0.84

0.80

0.80

Nagelkerke R square

0.22

0.23

0.21

0.25

p for the model

< 0.001

< 0.001

< 0.001

< 0.001

Non-clozapine group

 Age

1.03

1.04

1.04

1.04

 Sex

1.67

1.46

1.15

1.64

 Chlorpromazine equivalent

1.00

1.00

1.00

1.00

 ANT-attitude

1.05**

1.05**

1.04*

1.04*

 ANT-insight

1.00

1.00

0.99

1.00

 ANT-adverse effects

1.02

1.02

1.01

1.01

 BPRS_total

0.98

   

 BPRS_positive symptoms

 

0.98

  

 HONOS_total

  

1.03

 

 HONOS_behaviour

   

1.45

 HONOS_impairment

   

1.06

 HONOS_symptoms

   

0.79

 HONOS_social

   

1.34

 ADL

0.76

0.73

0.79

0.74

 IADL

1.07

1.16

1.11

1.11

 social functioning

0.85

0.85

0.79

0.84

 Nagelkerke R square

0.29

0.30

0.26

0.33

 p for the model

< 0.01

< 0.001

< 0.01

< 0.01

Clozapine group

Age

0.99

1.00

0.99

0.93

Sex

3.82

4.23

4.23

19.31

Chlorpromazine equivalent

1.00

1.00

1.00

1.00

ANT-attitude

1.04

1.04

1.05

1.02

ANT-insight

1.00

1.00

0.98

1.00

ANT-adverse effects

1.02

1.03

1.02

1.07

BPRS_total

0.99

   

BPRS_positive symptoms

 

0.96

  

HONOS_total

  

0.93

 

HONOS_behaviour

   

14.71

HONOS_impairment

   

0.39

HONOS_symptoms

   

0.78

HONOS_social

   

1.11

ADL

2.50

2.66

1.92

2.82

IADL

1.58

1.50

1.55

2.37*

social functioning

0.78

0.84

0.79

0.71

Nagelkerke R square

0.24

0.25

0.30

0.38

p for the model

0.31

0.28

0.21

0.15

  1. * p < 0.05 ** p < 0.01 ***p < 0.001
  2. In the presentation of categorical variables: a positive estimate indicates a better adherence for women. A positive estimate indicates a better adherence related to higher score in ANT-scales. High score in ANT -attitude, −insight and -side effect indicates positive attitudes toward medication, better sickness awareness and less experienced side effects. All models adjusted by age, gender, daily antipsychotic dose, ANT-insight, ANT-attitude and ANT-adverse effects