Table 1 Demographic and clinical features, alongside global brain volumes between ADHD with good methylphenidate response, ADHD with poor methylphenidate response
From: Regional brain volume predicts response to methylphenidate treatment in individuals with ADHD
Mean (SD) | ADHD with good response (n = 63) | ADHD with poor response (n = 16) | Statistics p valuea |
|---|---|---|---|
Age (in years) | 17.6 (10.1) | 17.1 (8.4) | 0.779 |
Age distribution |  |  | 0.840 (Fisher’s exact test) |
 6–10 years old (n, %) | 21 (33.3) | 4 (25.0) |  |
 11–20 years old (n, %) | 22 (34.9) | 7 (43.8) |  |
 21–30 years old (n, %) | 8 (12.7) | 3 (18.8) |  |
 31–40 years old (n, %) | 11 (17.5) | 2 (12.5) |  |
 42 years old (n, %) | 1 (1.6) | 0 (0.0) |  |
Gender, male (n, %) | 54 (85.7) | 11 (68.8) | 0.113 |
Handedness, right (n, %) | 62 (98.4) | 15 (93.8) | 0.289 |
Intelligence quotient (IQ) | |||
 Full-scale IQ | 107.3 (12.4) | 107.8 (10.6) | 0.779 |
 Verbal IQ | 107.9 (10.0) | 106.9 (8.6) | 0.779 |
 Performance IQ | 105.6 (14.0) | 108.4 (13.2) | 0.438 |
Subtype (n, %) |  |  | 0.666 (Fisher’s exact test) |
 Inattention type | 33 (52.4) | 10 (62.5) |  |
 Hyperactivity/impulsivity type | 1 (1.6) | 0 (0.0) | |
 Combined type | 29 (46.0) | 6 (37.5) | |
SNAP-IV | |||
 Inattention | 17.2 (5.5) | 17.7 (5.7) | 0.753 |
 Hyperactivity/impulsivity | 11.4 (6.6) | 10.3 (4.7) | 0.610 |
 Opposition-defiance | 10.3 (6.2) | 7.9 (4.3) | 0.166 |
 Inattention and hyperactivity | 28.6 (10.7) | 27.9 (7.0) | 0.985 |
Total volumes of gray matter (mm3) | 791.4 (67.1) | 798.5 (75.5) | 0.626 |
Total volumes of white matter (mm3) | 444.5 (57.4) | 445.1 (46.6) | 0.903 |
Total volumes of CSF (mm3) | 276.5 (70.4) | 246.9 (53.4) | 0.157 |
Total brain volumes (mm3) | 1236.0 (82.2) | 1243.6 (89.8) | 0.600 |
Total intra-cranial volumes (mm3) | 1512.4 (122.8) | 1490.5 (118.8) | 0.634 |