Factors related to age at depression onset: the role of SLC6A4 methylation, sex, exposure to stressful life events and personality in a sample of inpatients suffering from major depression

Table 2 Sex differences in the covariates and variables of interest

	n (m/f)	M_men	SD_men	M_women	SD_women	t	df	p_BH	d
Age	51/95	39.29	13.98	38.44	14.46	0.35	105.44	0.785	0.06
BMI	51/95	26.48	4.68	25.66	7.02	0.85	137.30	0.557	0.14
alcohol (grams/day)	49/89	7.72	20.76	2.06	6.69	1.86	53.55	0.193	0.37
cigarettes/day	50/94	6.96	10.53	4.62	7.18	1.41	73.81	0.306	0.26
DE antidepressants	46/78	41.66	31.08	33.81	26.93	1.43	84.04	0.306	0.27
DE neuroleptics	50/93	22.50	44.10	27.15	49.54	−0.58	110.86	0.634	− 0.10
BDI-II	50/89	29.61	12.16	33.74	10.58	−2.01	90.44	0.162	−0.36
MADRS	51/95	24.00	9.64	25.66	9.95	−0.98	105.18	0.534	−0.17
CLEQ	48/90	7.71	5.25	7.82	4.37	−0.13	82.16	0.898	−0.02
SEEKING	48/89	2.38	0.37	2.43	0.40	−0.74	104.04	0.569	−0.13
SADNESS	49/89	2.80	0.39	3.02	0.35	−3.17	91.05	0.028	−0.57
age at onset	51/95	29.43	14.31	23.80	12.05	2.39	88.47	0.089	0.43
SLC6A4 factor 1	46/81	−0.38	0.97	0.13	0.91	−2.95	88.79	0.028	−0.55
SLC6A4 factor 2	46/81	0.20	1.16	−0.12	0.95	1.58	79.43	0.280	0.30

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