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Table 5 Sensitivity analysis: Odds ratio (95% CI) for the association between sexual/physical abuse as a child and lifetime depression in adulthood

From: Sexual and physical abuse and depressive symptoms in the UK Biobank

Participants

Sample (no.)

Lifetime depression (%)

Childhood exposure

Odds ratio (95% CI) for lifetime depression

Unadjusted

Adjusted 1a

Adjusted 2b

All

40,829

20.3

Sexual abuse

2.12 (1.97, 2.29)

1.77 (1.64, 1.91)

1.58 (1.46, 1.72)

   

Physical abuse

2.00 (1.85, 2.16)

1.74 (1.60, 1.89)

1.45 (1.33, 1.58)

Women

22,683

24.5

Sexual abuse

2.00 (1.83, 2.18)

1.79 (1.63, 1.96)

1.61 (1.47, 1.77)

   

Physical abuse

2.03 (1.84, 2.25)

1.71 (1.54, 1.90)

1.45 (1.30, 1.62)

Men

18,146

15.1

Sexual abuse

1.90 (1.64, 2.20)

1.74 (1.50, 2.02)

1.52 (1.30, 1.78)

   

Physical abuse

2.00 (1.77, 2.28)

1.78 (1.57, 2.03)

1.45 (1.26, 1.66)

  1. aAdjusted for sex (if applicable), age, ethnicity, Townsend deprivation index, body mass index, and sexual/physical abuse as appropriate
  2. bAdditional adjustment for PHQ-9 depressive symptoms score