Table 14 Surface Under the Cumulative Ranking Curve (SUCRA)

 MADRS

0.82 (2)

0.49 (4)

0.81 (2)

0.86 (2)

0.28 (6)

0.27 (5)

0.04 (7)

 CGI-BP-S overall

0.85 (1)

0.45 (4)

0.63 (3)

0.75 (2)

N/A

0.19 (5)

0.10 (6)

 CGI-BP-S depression

0.95 (1)

N/A

0.58 (2)

N/A

0.41 (3)

N/A

0.06 (4)

 Response

0.96 (1)

0.54 (4)

0.6 (3)

0.86 (2)

0.23 (5)

0.2 (6)

0.1 (6)

 Remission (MADRS ≤12)

0.87 (1)

N/A

0.50 (3)

0.84 (2)

N/A

0.14 (4)

0.11 (5)

 Remission (MADRS ≤10)

0.88 (1)

0.60 (2)

N/A

N/A

N/A

N/A

0.00 (3)

 All-Cause

0.51 (4)

0.53 (4)

0.96 (1)

0.62 (3)

0.07 (7)

0.21 (6)

0.6 (3)

 Due to Efficacy

0.45 (4)

0.61 (3)

0.70 (3)

0.94 (1)

0.50 (4)

0.07 (7)

0.19 (6)

 Due to Adverse Events

0.77 (2)

0.52 (4)

0.56 (4)

0.13 (6)

0.18 (6)

0.5 (4)

0.84 (2)

 Change in Body Weight

0.66 (3)

0.45 (4)

0.0 (6)

0.20 (5)

0.75 (2)

N/A

0.91 (1)

 ≥ 7% Weight Gain

0.37 (5)

0.47 (4)

0.01 (6)

0.42 (4)

0.77 (2)

N/A

0.94 (1)

 Change in glucose

0.78 (1)

0.53 (3)

0.61 (2)

0.20 (5)

0.31 (5)

N/A

0.54 (3)

 Change in Triglycerides

0.76 (1)

0.49 (4)

0.40 (4)

0.09 (6)

0.53 (3)

N/A

0.70 (2)

 Change in Cholesterol

0.44 (4)

0.84 (1)

0.04 (6)

0.54 (3)

0.54 (3)

N/A

0.58 (3)

 Change in LDL

0.30 (6)

0.70 (2)

0.29 (5)

0.60 (2)

0.59 (2)

N/A

0.49 (4)

 Prolactin

0.01 (5)

0.30 (4)

N/A

0.58 (3)

0.73 (2)

N/A

0.85 (1)

 Somnolence

0.76 (2)

0.64 (3)

0.38 (5)

0.09 (7)

0.59 (3)

0.11 (6)

0.94 (1)

 EPS

0.22 (5)

0.45 (3)

N/A

0.28 (4)

0.57 (2)

N/A

0.99 (1)

 Akathisia

0.13 (4)

0.38 (3)

N/A

N/A

0.51 (2)

N/A

0.97 (1)

 Switch to Mania

0.74 (5)

0.41 (3)

0.29 (2)

0.13 (1)

0.88 (6)

NA

0.55 (4)