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Table 7 Odds Ratios for Discontinuation Due to Lack of Efficacy

From: Efficacy and tolerability of atypical antipsychotics for acute bipolar depression: a network meta-analysis

PLO

0.65 [0.19, 1.60]

0.50 [0.20, 1.04]

0.42 [0.14, 0.93]

0.23 [0.12, 0.40]

1.84 [0.54, 4.88]

0.77 [0.18, 2.17]

 

ARI

1.02 [0.21, 3.06]

0.86 [0.16, 2.68]

0.47 [0.11, 1.30]

3.79 [0.62, 13.01]

1.58 [0.21, 5.73]

  

CAR

1.01 [0.23, 2.83]

0.54 [0.17, 1.33]

4.41 [0.89, 14.22]

1.84 [0.31, 6.17]

   

OLA

0.68 [0.19, 1.84]

5.55 [1.03, 19.22]

2.32 [0.35, 8.31]

    

QUE

8.91 [2.12, 26.64]

3.72 [0.71, 11.61]

     

ZIP

0.57 [0.07, 2.06]

      

LUR

  1. Note: All-Cause Discontinuation results are on the top-right and Discontinuation Due to Adverse Events results are on the bottom-left. Numbers represent the odds ratio [95% credible interval]. In the top-right comparisons, the row treatment is the reference treatment. In the bottom-left, the column treatment is the reference category
  2. Abbreviations: PLO Placebo, ARI Aripiprazole, CAR Cariprazine, LUR Lurasidone, OLA Olanzapine, QUE Quetiapine, ZIP Ziprasidone