Venlafaxine vs. fluoxetine in postmenopausal women with major depressive disorder: an 8-week, randomized, single-blind, active-controlled study

Table 2 The mixed effect model analysis results of the two groups of HAMD-24,anxiety/somatization factor score

	Group	Time	Research center	Research center*Group	Time*group
HAMD(8w, FAS)
F	12.0	68.8	3.04	0.01	0.17
P	0.001	< 0.01	0.08	0.92	0.95
HAMD(8w, PP)
F	8.7	64.1	3.2	0.05	0.03
P	0.004	< 0.01	0.08	0.82	0.98
Anxiety/somatization factor(8w, FAS)
F	14.5	58.4	0.67	0.97	0.9
P	< 0.01	< 0.01	0.42	0.33	0.47

Data were analyzed using a mixed-effect model for repeated measures (MMRM). HAMD-24 24-item Hamilton Depression Rating Scale, FAS full analysis set, PP per-protocol analysis, * interaction

ISSN: 1471-244X