From: Sex differences between serum total bilirubin levels and cognition in patients with schizophrenia
 | Male (n = 268) | Female (n = 187) | ||||
---|---|---|---|---|---|---|
Cognition impairment group (n = 219) | Cognition normal group (n = 49) | P value | Cognition impairment group (n = 148) | Cognition normal group (n = 39) | P value | |
Age (years) | 48.68 ± 11.71 | 37.10 ± 11.57 | < 0.001* | 47.84 ± 13.78 | 33.90 ± 10.97 | < 0.001* |
BMI (kg/m2) | 24.57 ± 3.66 | 24.76 ± 3.92 | 0.749 | 24.25 ± 3.77 | 24.72 ± 4.34 | 0.53 |
Education (years) | 9.70 ± 3.12 | 12.76 ± 3.06 | < 0.001* | 9.74 ± 3.86 | 13.21 ± 2.60 | < 0.001* |
Hypertension (yes/no) | 30/189 | 0/49 | 0.002* | 8/140 | 2/37 | 1.000 |
Diabetes mellitus (yes/no) | 19/200 | 3/46 | 0.764 | 8/140 | 0/39 | 0.208 |
Total disease duration (months) | 264.68 ± 142.16 | 157.12 ± 135.05 | < 0.001* | 232.57 ± 167.08 | 122.20 ± 111.92 | < 0.001* |
Total PANSS score | 61.52 ± 17.54 | 61.00 ± 19.45 | 0.672 | 69.72 ± 18.91 | 55.31 ± 16.318 | < 0.001* |
TBIL (μmol/L) | 11.02 ± 4.77 | 14.98 ± 8.75 | 0.001* | 10.68 ± 4.22 | 9.96 ± 6.04 | 0.054 |
TC (mmol/L) | 4.46 ± 0.90 | 4.59 ± 0.81 | 0.095 | 4.54 ± 0.89 | 4.68 ± 1.36 | 0.696 |
TG (mmol/L) | 1.65 ± 1.24 | 1.74 ± 1.11 | 0.467 | 1.43 ± 0.92 | 2.08 ± 5.14 | 0.634 |
LDL (mmol/L) | 2.82 ± 0.76 | 2.98 ± 0.84 | 0.169 | 2.74 ± 1.05 | 2.58 ± 0.75 | 0.351 |
HDL (mmol/L) | 1.04 ± 0.26 | 1.29 ± 1.33 | 0.046* | 1.32 ± 0.40 | 1.36 ± 0.27 | 0.220 |
Mean chlorpromazine equivalent (mg) | 628.08 ± 379.8 | 578.97 ± 314.36 | 0.528 | 645.08 ± 378.02 | 614.42 ± 308.44 | 0.821 |