Exploring low grade inflammation by soluble urokinase plasminogen activator receptor levels in schizophrenia: a sex-dependent association with depressive symptoms

Table 4 Associations between CDSS and suPAR stratified by sex

	Males (n = 91)			Females (n = 72)
Items of CDSS interview	β^a	CI	p	β^a	95% CI	p
C1: Self described depression	−0.02	− 0.13 to 0.09	0.75	0.20	0.05 to 0.35	0.012
C2: Hopelessness	0.04	−0.08 to 0.16	0.47	0.20	0.05 to 0.36	0.011
C3: Self depreciation	0.03	−0.08 to 0.13	0.61	0.20	0.07 to 0.32	0.002
C4: Guilty ideas of reference	0.19	0.03 to 0.35	0.02	0.21	0.06 to 0.36	0.006
C5: Pathological guilt	0.09	−0.09 to 0.26	0.34	0.22	0.10 to 0.35	0.001
C6: Morning depression	0.01	−0.12 to 0.15	0.86	0.22	0.07 to 0.36	0.004
C7: Early wakening	0.07	−0.05 to 0.19	0.27	0.18	0.06 to 0.31	0.005
C8: Suicide	−0.17	− 0.34 to − 0.00	0.045	0.31	0.13 to 0.48	0.001
C9: Observed depression	0.06	−0.10 to 0.22	0.44	0.13	−0.07 to 0.32	0.21

Note: suPAR soluble urokinase Plasminogen Activator Receptor (ng/ml), CDSS Calgary Depression Scale for Schizophrenia (0–27), CI Confidence Interval, β = beta coefficient, CI confidence interval
^aAdjusted for age, current tobacco smoking, high sensitivity C-reactive protein and body mass index

ISSN: 1471-244X