Characteristics of the corpus callosum in chronic schizophrenia treated with clozapine or risperidone and those never-treated

Table 2 Corpus callosum volumes (mm³) in CT-SCZ, RT-SCZ, NT-SCZ and HCs

Corpus callosum	CT-SCZ, N = 23 Mean ± SD	RT-SCZ, N = 19 Mean ± SD	NT-SCZ, N = 23 Mean ± SD	HCs, N = 35 Mean ± SD	F value	p value	Post-hoc analyses
Corpus callosum	CT-SCZ, N = 23 Mean ± SD	RT-SCZ, N = 19 Mean ± SD	NT-SCZ, N = 23 Mean ± SD	HCs, N = 35 Mean ± SD	F value	p value	NT-SCZ vs. HCs	NT-SCZ vs. RT-SCZ	NT-SCZ vs. CT- SCZ	RT-SCZ vs. CT- SCZ	RT-SCZ vs. HCs	CT-SCZ vs. HCs
Anterior	916.73 ± 145.59	866.72 ± 155.71	831.76 ± 110.77	845.43 ± 124.69	0.601	0.616	NS	NS	NS	NS	NS	NS
Mid-anterior	530.28 ± 135.11	590.23 ± 126.91	460.38 ± 76.92	611.49 ± 150.69	6.380	0.001	< 0.001***	0.024*	NS	NS	NS	0.012*
Central	546.32 ± 152.74	538.48 ± 123.73	490.27 ± 114.93	600.16 ± 139.44	3.318	0.023	0.006**	NS	NS	NS	NS	NS
Mid-posterior	479.59 ± 96.39	500.46 ± 107.27	454.47 ± 87.86	503.92 ± 78.22	1.287	0.284	NS	NS	NS	NS	NS	NS
Posterior	942.36 ± 157.09	949.00 ± 172.78	835.62 ± 128.31	900.63 ± 148.86	1.995	0.120	NS	NS	NS	NS	NS	NS
Total	3415.29 ± 524.04	3444.89 ± 553.07	3072.52 ± 363.73	3450.67 ± 414.81	3.213	0.027	0.004**	NS	NS	NS	NS	NS

Note: CT-SCZ clozapine-treated schizophrenia patients, RT-SCZ risperidone-treated schizophrenia patients, NT-SCZ never-treated schizophrenia patients, HCs healthy controls, NS not significant, *, Significant group difference at P < 0.05; **, P < 0.01; ***, P < 0.001

ISSN: 1471-244X