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Table 3 Summary of Affinity and CYP450 Metabolic Pathways [18]ǂ

From: Pharmacist assessment of drug-gene interactions and drug-induced phenoconversion in major depressive disorder: a case report

  1. MedWise™ depicts the various degrees of binding affinity of a substrate for a specific enzyme using different colors (e.g., light yellow for weak affinity and dark yellow for moderate affinity. The percentages listed correspond to the use of the metabolic pathway for the substrate
  2. Legend:  View full size image
  3. Abbreviations: CYP Cytochrome P450
  4. ǂOnly CYP-metabolized oral drugs are displayed