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Table 6 Comparison of cognitive test scores in patients with different genotypes of rs12294045

From: Polymorphism of rs12294045 in EAAT2 gene is potentially associated with schizophrenia in Chinese Han population

Subtests

 

rs12294045

 

F

Ρ

Ρ 1

Ρ 2

Ρ 3

 

CT(n = 96)

CC(n = 116)

TT(n = 20)

 

TMT-A

45.23 ± 7.86

46.28 ± 11.97

47.95 ± 7.54

0.704

0.495

0.442

0.274

0.500

Symbol Coding

42.00 ± 10.56

40.98 ± 10.10

44.60 ± 11.07

1.113

0.330

0.473

0.308

0.149

Category Fluency

47.75 ± 11.32

47.35 ± 11.25

48.55 ± 10.88

0.105

0.901

0.805

0.772

0.664

CPT-IP

41.84 ± 11.11

42.05 ± 10.75

45.25 ± 13.08

0.823

0.441

0.914

0.213

0.228

LNS

43.76 ± 10.97

46.96 ± 11.32

50.75 ± 9.89

4.184

0.016

0.042

0.011

0.149

WMS-III

44.34 ± 12.03

44.68 ± 12.93

47.10 ± 12.63

0.413

0.662

0.914

0.373

0.399

HVLT-R

42.22 ± 12.18

44.94 ± 10.88

48.80 ± 11.08

3.222

0.042

0.098

0.020

0.154

BVMT-R

43.89 ± 11.79

43.16 ± 11.16

44.30 ± 13.07

0.192

0.826

0.598

0.884

0.655

NAB-MAZES

43.02 ± 8.99

42.94 ± 11.05

42.65 ± 10.70

0.013

0.987

0.914

0.883

0.930

MSCEIT

47.03 ± 12.30

48.09 ± 11.91

51.75 ± 14.55

1.222

0.297

0.568

0.120

0.209

  1. Note: Bolded indicates statistically significant (p < 0.05)
  2. Ρ 1 represents the comparison between CT genotype patients and CC genotype patients; Ρ 2 represents the comparison between CT genotype patients and TT genotype patients; Ρ 3 represents the comparison between CC genotype patients and TT genotype patients.(TMT-A Trail Making Test A, CPT-IP Continuous Performance Test-Identical Pairs, LNS Letter-Number Span Test, WMS-III Wechsler Memory Scale-Third Edition, HVLT-R Hopkins Verbal Learning Test-Revised, BVMT-R Brief Visuospatial Memory Test-Revised, NAB Neuropsychological Assessment Battery, MSCEIT Mayer-Salovey-Caruso Emotional Intelligence Test).