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Table 1 Cognitive and developmental symptoms in the childhood psychiatric history of adults presenting schizophrenia and mood spectrum disorder (n=205)

From: The mood disorder spectrum vs. schizophrenia decision tree: EDIPHAS research into the childhood and adolescence of 205 patients

 

Schizophrenia n=123

Mood spectrum disorder n=82

Chi2/Fisher

Symptoms

Number of Patients (% of the population)

Age at Onset (in years) Mean (SD)

Number of Patients (% of the population)

Age at Onset (in years) Mean (SD)°

p value

Cognitive and developmental symptoms

     

  Low IQ (<69)

24 (19.5%)

-

0 (0%)

-

<0.0001*

  High IQ (>120)

1 (0.8%)

-

2 (2.4%)

-

0.565

  Heterogeneous or discordant IQ

12 (9.8%)

-

1 (1.2%)

-

0.014*

  Delayed psychomotor development

17(13.8%)

-

7 (8.5%)

-

0.249

  Lateralisation disturbances

2 (1.6%)

-

1 (1.2%)

-

1.000

  Time and space orientation disturbances

14 (11.4%)

-

5 (6.1%)

-

0.071

  Other psychomotor disturbances

12 (9.8%)

-

9 (11%)

-

0.778

  Speech/language disorders and delay

21 (17.1%)

-

7 (8.5%)

-

0.081

  Articulation disorders

5 (4.1%)

-

4 (4.9%)

-

1.000

  Written language disorders

13 (10.6%)

-

9 (11%)

-

0.927

  Mathematics disorders

9 (7.3%)

-

4 (4.9%)

-

0.483

  Learning disorders not otherwise specified

11 (8.9%)

-

11 (13.4%)

-

0.311

  Drop in grades and school performance

63 (51.2%)

14.3 (2.6)

32 (39%)

13.5 (3)

0.086

  Educational underachievement or special educational needs

89 (72.4%)

11.5 (4.5)

30 (36.6%)

12.1 (4)

<0.001*

  Attention and concentration deficit

46 (37.4%)

11.7 (4.6)

26 (31.7%)

13.6 (3.4)

0.403

  Psycho-affective immaturity

25 (22.8%)

12.3 (3.9)

23 (28%)

12.4 (4.3)

0.391

  Tics

13 (10.6%)

11.1 (3.7)

3 (3.7%)

11 (5.2)

0.071

  Muteness

16 (13%)

12.9 (4.1)

4 (4.9%)

9 (3.6)

0.055

  Stuttering

3 (2.4%)

11.3 (6.4)

0 (0%)

-

0.276

  1. Legends: SD Standard Deviation; * significant result with p<0.05; the Chi2 or Fisher’s exact test was applied