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Table 5 Associations between measures of preoperative anxiety and the desire for anxiolytic medication

From: Patients’ desires for anxiolytic premedication – an observational study in adults undergoing elective surgery

Variable

Desire for anxiolytic medication

Yes a

On request a

B

p

OR [95 %CI]

B

p

OR [95 %CI]

All patients

  Self-reported anxiety (no vs. yes)

1.46

< 0.001

4.30 [3.16, 5.84]

1.26

< 0.001

3.53 [2.52, 4.95]

  APAIS total anxiety score

0.25

< 0.001

1.28 [1.22, 1.34]

0.20

< 0.001

1.22 [1.16, 1.29]

  APAIS anxiety dimensions

    Bivariate

      APAIS anesthesia anxiety score

0.46

< 0.001

1.58 [1.44, 1.73]

0.39

< 0.001

1.47 [1.33, 1.63]

      APAIS surgery anxiety score

0.33

< 0.001

1.40 [1.30, 1.50]

0.27

< 0.001

1.30 [1.21, 1.41]

    Multivariate b

      APAIS anesthesia anxiety score

0.33

< 0.001

1.39 [1.25, 1.54]

0.28

< 0.001

1.32 [1.18, 1.49]

      APAIS surgery anxiety score

0.19

< 0.001

1.21 [1.11, 1.31]

0.14

0.002

1.15 [1.05, 1.27]

  NRS total anxiety score

0.19

< 0.001

1.21 [1.17, 1.25]

0.16

< 0.001

1.18 [1.13, 1.22]

  NRS anxiety dimensions

    NRS anesthesia anxiety score

0.34

< 0.001

1.41 [1.32, 1.50]

0.28

< 0.001

1.32 [1.23, 1.42]

    NRS surgery anxiety score

0.30

< 0.001

1.35 [1.27, 1.43]

0.27

< 0.001

1.30 [1.22, 1.39]

    Multivariate b

      NRS anesthesia anxiety score

0.21

< 0.001

1.24 [1.14, 1.34]

0.14

< 0.001

1.15 [1.05, 1.27]

      NRS surgery anxiety score

0.17

< 0.001

1.19 [1.10, 1.28]

0.18

< 0.001

1.20 [1.10, 1.30]

Patients who reported anxiety (no vs. yes)

  APAIS total anxiety score

0.17

< 0.001

1.19 [1.10, 1.28]

0.11

0.008

1.12 [1.03, 1.21]

  APAIS anxiety dimensions

    Bivariate

      APAIS anesthesia anxiety score

0.28

< 0.001

1.32 [1.16, 1.50]

0.22

0.002

1.24 [1.08, 1.42]

      APAIS surgery anxiety score

0.17

0.004

1.18 [1.06, 1.33]

0.07

0.237

1.08 [0.95, 1.22]

  Multivariate b

      APAIS anesthesia anxiety score

0.25

< 0.001

1.29 [1.13, 1.47]

0.21

0.004

1.23 [1.07, 1.42]

      APAIS surgery anxiety score

0.10

0.086

1.11 [0.99, 1.25]

0.03

0.651

1.03 [0.91, 1.17]

NRS total anxiety score

0.14

< 0.001

1.12 [1.09, 1.23]

0.10

0.002

1.10 [1.04, 1.18]

NRS anxiety dimensions

      NRS anesthesia anxiety score

0.21

< 0.001

1.23 [1.12, 1.35]

0.13

0.011

1.14 [1.03, 1.26]

      NRS surgery anxiety score

0.17

< 0.001

1.19 [1.08, 1.30]

0.13

0.013

1.14 [1.03, 1.26]

  Multivariate b

      NRS anesthesia anxiety score

0.17

0.001

1.19 [1.08, 1.31]

0.10

0.065

1.11 [0.99, 1.23]

      NRS surgery anxiety score

0.11

0.027

1.12 [1.01, 1.24]

0.10

0.071

1.11 [0.99, 1.23]

Patients who reported no anxiety (no vs. yes)

  APAIS total anxiety score

0.21

< 0.001

1.23 [1.13, 1.35]

0.18

< 0.001

1.20 [1.08, 1.32]

  APAIS anxiety dimensions

    Bivariate

      APAIS anesthesia anxiety score

0.43

< 0.001

1.53 [1.27, 1.86]

0.34

0.002

1.41 [1.14, 1.74]

      APAIS surgery anxiety score

0.26

< 0.001

1.29 [1.13, 1.48]

0.24

0.002

1.27 [1.10, 1.48]

    Multivariate b

      APAIS anesthesia anxiety score

0.32

0.007

1.37 [1.09, 1.73]

0.21

0.119

1.23 [0.95, 1.59]

      APAIS surgery anxiety score

0.14

0.109

1.15 [0.97, 1.36]

0.16

0.079

1.18 [0.98, 1.41]

NRS total anxiety score

0.19

< 0.001

1.21 [1.12, 1.31]

0.19

< 0.001

1.21 [1.12, 1.32]

NRS anxiety dimensions

      NRS anesthesia anxiety score

0.37

< 0.001

1.45 [1.24, 1.68]

0.35

< 0.001

1.41 [1.19, 1.68]

      NRS surgery anxiety score

0.30

< 0.001

1.35 [1.18, 1.53]

0.32

< 0.001

1.37 [1.19, 1.58]

    Multivariate b

      NRS anesthesia anxiety score

0.22

0.057

1.25 [0.99, 1.57]

0.15

0.232

1.16 [0.91, 1.48]

      NRS surgery anxiety score

0.17

0.085

1.18 [0.98, 1.42]

0.23

0.024

1.26 [1.03, 1.53]

  1. APAIS Amsterdam preoperative anxiety and information scale, NRS numeric rating scale. a Reference category: No desire for anxiolytic medication. b Models included both anxiety dimensions simultaneously to examine whether anesthesia anxiety and surgery anxiety have unique associations with the desire for anxiolytic medication.
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BMC Psychiatry

ISSN: 1471-244X

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