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Table 2 Adverse effects reported by patients in this study

From: A retrospective case notes review of the effectiveness and tolerability of metoclopramide in the treatment of clozapine-induced hypersalivation (CIH)

Patient identifier

Adverse effects

Onset of symptoms

Previous history if EPSE(s)

Concomitant medications

Did adverse reactions lead to cessation of metoclopramide treatment?

4

Leg stiffness and tremor

2 months

Yes

Clozapine Sodium valproate Trihexyphenidyl

No

5

Resting tremor in hands and feet Shuffling gait

9 months

Yes

Clozapine Sodium valproate Paracetamol Senna Promethazine Levothyroxine Simvastatin

No

6

Tremor and agitation

2 months

Yes

Clozapine Aripiprazole Sodium valproate Promethazine Lactulose Senna Atropine drops

Yes

10

Resting bilateral tremor

4 months

Yes

Clozapine Aripiprazole Sodium valproate Amisulpride Lithium Diazepam Omeprazole

No

13

Nausea and vomiting

1 day

Yes

Clozapine Sodium valproate

Yes