Fig. 2

Mean (standard error) symptom assessment scale scores at each visit over the 3 months of vortioxetine treatment (observed cases): (A) MADRS total score; (B) MADRS anhedonia factor score; (C) PHQ-9 total score; and (D) PDQ-D total score. *p < 0.001 for all paired comparisons over the three visits. MADRS = Montgomery–Åsberg Depression Rating Scale; PDQ-D = 20-item Perceived Deficits Questionnaire–Depression; PHQ-9 = 9-item Patient Health Questionnaire