Fig. 3

Logistic Regression modeling of likelihood of clinically significant improvement in depressive and anxiety symptom scores. A Baseline GAD-7 score and diagnosis of an anxiety disorder predict lower odds of a clinically significant improvement in depression symptom severity. B Graphical illustration of the predicted impact of baseline GAD-7 and the presence versus absence of an anxiety disorder diagnosis based upon simulation data. C Interaction of female sex with baseline GAD-7 score in the likelihood of clinically significant improvement in anxiety. D There is little relationship between baseline score and likelihood of improvement in anxious symptoms for men, but a clear sigmoidal curve for female patients showing a higher predicted likelihood of improvement with increasing baseline GAD-7 score