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Table 4 Linear mixed effects analysis for structural connectivity global metrics. Exact values reported, but findings are interpreted only if significant after false discovery rate corrections

From: Brain connectomes in youth at risk for serious mental illness: an exploratory analysis

 

Model 0

AIC

BIC

Model 1

AIC

BIC

χ2

Sig

Model 2

AIC

BIC

χ2

Sig

 

-2LL

  

-2LL

  

change

 

-2LL

  

change

 

Connectome density

-546.75

-540.75

-531.32

-556.60

-524.60

-474.33

-9.85

n.s

-560.19

-520.19

-457.35

-3.59

n.s

Connectome intensity

-788.53

-782.53

-773.11

-811.86a

-779.86

-729.60

-23.33

0.05

-816.87

-776.87

-714.04

-5.01

n.s

Assortativity (z-score)

784.49

790.49

799.91

763.20

795.20

845.47

-21.29

n.s

755.34

795.34

858.17

-7.86

n.s

Hierarchy (z-score)

621.46

627.46

636.88

613.25

645.25

695.52

-8.21

n.s

610.69

650.69

713.52

-2.56

n.s

Network efficiency

 Global

-732.60

-726.60

-717.17

-742.24

-710.24

-659.97

-9.64

n.s

-745.92

-705.92

-643.09

-3.68

n.s

 Local

-982.91

-976.91

-967.48

-1001

-969

-918.73

-18.09

n.s

-1001.85

-961.85

-899.02

-0.85

n.s

Small world

 Clustering coefficient

-759.99

-753.99

-744.56

-777.83

-745.83

-695.56

-17.84

n.s

-778.59

-738.59

-675.75

-0.76

n.s

 ϒ (Gamma)

-164.63

-158.63

-149.20

-174.73

-142.73

-92.47

-10.10

n.s

-179.82

-139.82

-76.99

-5.09

n.s

 λ (Lambda)

-1317.11

-1311.11

-1301.70

-1334.67

-1302.67

-1252.50

-17.56

n.s

-1339.10

-1299.10

-1236.38

-4.43

n.s

 Shortest path length

-466.93

-460.93

-451.50

-477.080

-445.080

-394.81

-10.15

n.s

-480.99

-440.99

-378.16

-3.91

n.s

 σ (Sigma)

-189.12

-183.12

-173.70

-198.99

-166.99

-116.73

-9.87

n.s

-203.93

-163.93

-101.09

-4.94

n.s

 Synchronization (z-score)

1162.38

1168.38

1177.80

1148.88

1180.88

1231.15

-13.5

n.s

1143.95

1183.95

1246.79

-4.93

n.s

  1. Model 0 = no fixed factors; Model 1 fixed factor = age; Model 2 fixed factor = age, group
  2. aSignificant effect of age