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Table 2 HRU among respondents with depression versus without depression diagnosis and across severity groups – Multivariable results

From: Humanistic and economic burden associated with depression in the United States: a cross-sectional survey analysis

HRU in the past 6 months

Respondents without depression diagnosisb

n = 30,478

Respondents with depression diagnosisa

Total (all symptom levels)

n = 8853

No/minimal symptoms

n = 1876

Mild symptoms

n = 2801

Moderate symptoms

n = 1938

Moderately severe symptoms

n = 1376

Severe symptoms

n = 862

Healthcare provider visits, mean ± SE

2.41 ± 0.03

3.61 ± 0.08‡

5.46 ± 0.17

5.60 ± 0.14

5.78 ± 0.17

6.23 ± 0.22**

6.50 ± 0.3**

ER visits, mean ± SE

0.09 ± 0

0.14 ± 0.01‡

0.25 ± 0.02

0.23 ± 0.01

0.26 ± 0.02

0.31 ± 0.02*

0.34 ± 0.03**

Hospitalizations, mean ± SE

0.04 ± 0

0.08 ± 0.01‡

0.11 ± 0.01

0.10 ± 0.01

0.11 ± 0.01

0.13 ± 0.02

0.16 ± 0.02*

  1. Results are based on generalized linear regression models controlling for demographics, health characteristics, and comorbidities as covariates
  2. aRespondents with depression diagnosis: those who self-reported physician diagnosis of depression and reported experiencing depression in the past 12 months
  3. bRespondents without depression diagnosis: those who had no self-reported physician diagnosis of depression, reported not experiencing depression in the past 12 months, and had PHQ-9 scores ≤ 4
  4. *P-value < 0.050 for comparison vs ‘no/minimal symptoms’ severity group
  5. **P-value < 0.010 for comparison vs ‘no/minimal symptoms’ severity group
  6. ‡P-value < 0.001 for comparison vs ‘without depression diagnosis’ group
  7. ER Emergency room, HRU Healthcare resource utilization, SE Standard error