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Table 1 Baseline characteristics and demographics of CATIE study participants by PANSS Item G12 insight rating

From: Impaired insight in schizophrenia: impact on patient-reported and physician-reported outcome measures in a randomized controlled trial

Characteristic

All Patients N = 1431

PANSS Insight Item Rating 1 to 4 (Absent to Moderate) n = 1293 (90%)

PANSS Insight Item Rating 5 to 7 (Moderate-Severe to Extreme) n = 138 (10%)

P value*

Treatment for phase 1/1A, n (%a)

   

0.7710

 Olanzapine

330 (23.1)

304 (92.1)

26 (7.9)

 

 Perphenazine

256 (17.9)

228 (89.1)

28 (10.9)

 

 Quetiapine

330 (23.1)

298 (90.3)

32 (9.7)

 

 Risperidone

333 (23.3)

299 (89.8)

34 (10.2)

 

 Ziprasidone

182 (12.7)

164 (90.1)

18 (9.9)

 

Age, y, mean (SD)

40.6 (11.1)

40.7 (11.0)

39.6 (12.1)

0.2815

Age group, n (%a)

   

0.0998

 18–35 years

449 (31.4)

395 (88.0)

54 (12.0)

 

 36–45 years

476 (33.3)

438 (92.0)

38 (8.0)

 

 46+ years

506 (35.4)

460 (90.9)

46 (9.1)

 

Sex, n (%a)

   

0.0820

 Male

1063 (74.3)

952 (89.6)

111 (10.4)

 

 Female

368 (25.7)

341 (92.7)

27 (7.3)

 

Race, n (%a)

   

0.2376

 White

875 (61.1)

789 (90.2)

86 (9.8)

 

 Black

506 (35.4)

462 (91.3)

44 (8.7)

 

 Other

50 (3.5)

42 (84.0)

8 (16.0)

 

Marital status, n (%a)

   

0.0478

 Married

166 (11.6)

156 (94.0)

10 (6.0)

 

 Previously married

414 (28.9)

381 (92.0)

33 (8.0)

 

 Never married

851 (59.5)

756 (88.8)

95 (11.2)

 

Patient education, n (%a)

   

0.2445

  < 12 years

365 (25.5)

336 (92.1)

29 (7.9)

 

 12 years

506 (35.4)

449 (88.7)

57 (11.3)

 

  > 12 years

560 (39.1)

508 (90.7)

52 (9.3)

 

Employed, n (%a)

   

0.3161

 No

1213 (84.8)

1092 (90.0)

121 (10.0)

 

 Yes

218 (15.2)

201 (92.2)

17 (7.8)

 

Lives alone, n (%a)

   

0.2536

 No

1084 (75.8)

974 (89.9)

110 (10.1)

 

 Yes

347 (24.2)

319 (91.9)

28 (8.1)

 
  1. Abbreviations: PANSS Positive and Negative Syndrome Scale, SD standard deviation
  2. *For comparisons between patients with PANSS Item G12 ratings of 1–4 versus 5–7, t tests were performed on continuous variables, and Chi-square tests were performed on categorical values
  3. aFor “All Patients,” percentages indicate proportion of total patients. For PANSS Insight subgroups, percentages indicate proportions of patients with the given characteristic