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Table 2 Demographic and clinical characteristics of MDD patients stratified by whether they experienced remission or not

From: RPS6KA5 methylation predict response to 6-week treatment for adolescent MDD patients

Characteristic

Remission

(n = 9)

Non-remission

(n = 75)

F or χ2

p

Demographic characteristics

  Age (years)

15.00 ± 1.32

14.45 ± 1.47

0.249

0.291

  Sex (Male/Female)

3/6

11/64

2.016

0.168

  Level of education (Junior/Senior)

5/4

43/32

0.01

1

Clinical characteristics

  CCSQ total score

146.78 ± 39.28

137.41 ± 39.81

0.004

0.506

  Peer bullying

30.56 ± 15.44

28.34 ± 11.99

1.798

0.613

  Childhood abuse and neglect

68.00 ± 20.72

63.98 ± 22.23

0.451

0.607

  Adverse childhood experience

48.22 ± 13.07

45.10 ± 13.35

0.000

0.508

  Baseline BDI score

30.78 ± 6.76

34.88 ± 9.03

0.213

0.191

  Antidepressant dosea (mg)

36.94 ± 11.94

40.15 ± 16.61

1.354

0.577

  RPS6KA5 methylation percentage

7.39 ± 1.99

5.19 ± 2.99

2.825

0.035

  1. a The antidepressant dose was calculated in fluoxetine equivalents
  2. Values are expressed as n or as means ± standard errors, unless indicated otherwise. Raw data are in Supplementary Table 2