Alterations of functional connectivity of the lateral habenula in subclinical depression and major depressive disorder

Table 1 Demographic and clinical characteristic of three groups of participants

Characteristics	MDD (n = 38)	SD (n = 26)	HC (n = 33)	p-value
Gender, female/male	27/11	16/10	16/17	0.150^a
Age, years	21.13 ± 6.17	19.65 ± 1.77	19.24 ± 0.94	0.120^b
Education, years	12.94 ± 2.60	13.36 ± 0.92	13.18 ± 0.87	0.492^b
BDI-II score	-	22.46 ± 7.73	1.55 ± 1.44	< 0.001^c
HAMD score	21.51 ± 4.58	-	-	-
RMS FD	0.45 ± 0.02	0.54 ± 0.06	0.52 ± 0.06	0.177^b

Abbreviations: MDD major depressive disorder, SD subclinical depression, HC healthy control, BDI-II Baker Depression Inventory-II, HAMD Hamilton Depression, RMS FD root mean squared framewise displacement
^ap value obtained by chi-squared test
^bp values obtained by one-way analysis of variance tests
^cp value obtained by two-sample t-test

ISSN: 1471-244X