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Table 1 Sample characteristics of 282 patients with MDD

From: Association between childhood trauma and medication adherence among patients with major depressive disorder: the moderating role of resilience

Variables

Total, n (%)

Optimal adherence

Suboptimal adherence

P Value#

Total

282 (100)

48 (17.0)

234 (83.0)

 

Age (years), median (IQR)

25.0 (9.0)

26.0 (9.0)

24.0 (10.0)

0.288

Sex

 Male

95 (33.7)

13 (27.1)

82 (35.0)

0.288

 Female

187 (66.3)

35 (72.9)

152 (65.0)

 

Marital status

 Unmarried

199 (73.2)

35 (74.5)

164 (72.9)

0.233

 Married

61 (22.4)

8 (17.0)

53 (23.6)

 

 Divorced/Widowed

12 (4.4)

4 (8.5)

8 (3.6)

 

 Missing data

10

   

Education level

 Junior high school or below

50 (18.1)

16 (34.0)

34 (14.8)

 < 0.001

 Senior high school

74 (26.8)

16 (34.0)

58 (25.3)

 

 College or above

152 (55.1)

15 (31.9)

137 (59.8)

 

 Missing data

6

   

Living arrangement

 Living alone

61 (22.3)

10 (21.3)

51 (22.5)

0.664

 Living with families

167 (60.9)

27 (57.4)

140 (61.7)

 

 Living with others

46 (16.8)

10 (21.3)

36 (15.9)

 

 Missing data

8

   

HSS

 Excellent or very good

106 (41.6)

18 (43.9)

88 (41.1)

0.870

 Good

73 (28.6)

10 (24.4)

63 (29.4)

 

 Fair

76 (29.8)

13 (31.7)

63 (29.4)

 

 Missing data

27

   

Current cigarette smoking

 No

130 (47.3)

26 (56.5)

104 (45.4)

0.169

 Yes

145 (52.7)

20 (43.5)

125 (54.6)

 

 Missing data

7

   

Current alcohol drinking

 No

237 (84.9)

41 (89.1)

196 (84.1)

0.385

 Yes

42 (15.1)

5 (10.9)

37 (15.9)

 

 Missing data

3

   

Exercise habit per week

 No

171 (63.1)

29 (64.4)

142 (62.8)

0.838

 Yes

100 (36.9)

16 (35.6)

84 (37.2)

 

 Missing data

11

   

HAMD-17 scores, mean (SD)

17.84 (5.02)

17.34 (5.03)

20.19 (4.28)

 < 0.001

GAD-7 scores, median (IQR)

14.0 (8.0)

13.0 (9.0)

17.0 (5.0)

0.005

Suicidal ideation

 No

192 (68.8)

24 (51.1)

168 (72.4)

0.004

 Yes

87 (31.2)

23 (48.9)

64 (27.6)

 

 Missing data

3

   

Suicidal attempt

 No

249 (88.9)

35 (72.9)

214 (92.2)

 < 0.001

 Yes

31 (11.1)

13 (27.1)

18 (7.8)

 

 Missing data

2

   

Insomnia

 None

40 (14.3)

3 (6.3)

37 (16.0)

0.020

 Subthreshold

85 (30.5)

9 (18.8)

76 (32.9)

 

 Moderate

109 (39.1)

24 (50.0)

85 (36.8)

 

 Severe

45 (16.1)

12 (25.0)

33 (14.3)

 

 Missing data

3

   

SSI pain-related items

 Without pain

90 (32.0)

25 (52.1)

65 (27.9)

 < 0.001

 With pain

192 (68.0)

23 (47.9)

168 (72.1)

 

CD-RISC scores, median (IQR)

37.0 (18.0)

38.0 (18.0)

31.0 (14.0)

0.001

CTQ total scores, median (IQR)

46.0 (16.0)

45.0 (17.0)

49.0 (15.0)

0.012

CTQ scores of physical abuse, median (IQR)

6.0 (3.0)

5.0 (2.0)

7.0 (3.0)

0.031

CTQ scores of emotional abuse, median (IQR)

9.0 (5.0)

9.0 (6.0)

10.0 (3.0)

0.082

CTQ scores of sexual abuse, median (IQR)

5.0 (0.0)

5.0 (0.0)

5.0 (1.0)

0.015

CTQ scores of physical neglect, median (IQR)

8.0 (5.0)

8.0 (5.0)

10.0 (7.0)

0.006

CTQ scores of emotional neglect, median (IQR)

15.0 (8.0)

15.0 (8.0)

17.0 (8.0)

0.088

  1. Abbreviations: SD Standard, IQR interquartile range, HSS Household socioeconomic status, HAMD-17 17-item hamilton rating scale for depression, GAD-7 the generalized anxiety disorder scale-7, SSI Somatic symptoms inventory, CD-RISC Connor-davidson resilience scale, CTQ Childhood trauma questionnaire-28 item short form
  2. #Chi-squared tests were used for categorical variables, t test was used for HAMD-17 scores data, and Wilcoxon’s rank-sum tests were used for other continuous data