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Table 1 Reports of AH during patient’s (pt) main admission

From: Varenicline induced auditory hallucinations in a young female with bipolar disorder: a case report

Date

Noted Auditory Hallucinations

Day 5

Patient (pt) feels safe in hospital and denies any auditory/visual hallucinations

Day 14

Denies hearing any AH and states “I only hear them when I’m manic”

Day 15

Had reportedly voiced AH to nursing staff, and she states during notes “I sometimes hear a mumble” but it did not appear to be overtly hallucinations

Day 17

AH present. Pt states voices occur with her mania. Reports voices tell her what to wear when she is deciding on an outfit to put on. Reports to hear voices while walking in the hallway. States she turns her head to look, no one is there. Reports she hears voices coming from people sitting beside her. When she looks, their mouths are not moving, and she continues to hear the voices. Pt states listening to loud music helps her cope with AH.—pt states voices are “louder”. “States she had auditory hallucinations earlier in the day of a derogatory nature-states they are voices of people she knows. Denies they are command. Reports previous medications helpful reducing them. Settled on unit. Loxapine 10 mg, Ativan 2 mg, and Seroquel 50 mg po prn with evening medications

Day 18

AH present. Pt reports AH are “quieter” than yesterday. Pt denies AH to be derogatory. AH are not command in nature. As per nursing notes, patient endorsed having an upset stomach and AH that tell her how to dress. Coping mechanism being listening to music. AH endorsed as command. Pt absconded while on a group walk. Returned on her own on the same day.

Day 19

Asked about AH today—“nothing yet today” Reports that AH “are not present this morning”- she states that she thinks they were because “of that new medication for stopping smoking that they gave me”; reports that the AH have decreased since stopping the same. No other voiced or observed perceptual disturbances present. No formal cognitive testing completed; however, the patient was attentive throughout the interview and there were no observed memory impairments present. Insight is increasingly becoming fuller as she becomes more self-aware and experiencing less manic symptoms -recognizes that her previous drug use has [led] to these current problems and that she is better without them

Day 20

Pt reports AH occurring in the middle of the day. Pt unsure of [the] same being voices or overhearing nursing staff speak. Student Nurse—Brief AH reported; however [the] same was not bothersome. From MSE—Perceptual Abnormality—Denies

  1. Varenicline dosage was initiated on Day 14 and discontinued on Day 18 following concerns of persistent AH reported by the patient