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Fig. 5 | BMC Psychiatry

Fig. 5

From: Assessing the expression of two post-transcriptional BDNF regulators, TTP and miR-16 in the peripheral blood of patients with Schizophrenia

Fig. 5

Schematic representation of the mechanism of action of TTP in collaboration with miR-16 in effect on ARE. TTP is an RBP that regulates the expression of target mRNAs post-transcriptionally by acting on ARE and recruiting deadenylation and degradation factors. TTP is assisted in this operation by miR-16 in the form of a RISC complex. MiR-16 can also affect gene expression through microRNA response elements (MRE).

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BMC Psychiatry

ISSN: 1471-244X

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