Table 3 Association of the rs2253206, rs10932201, and rs162209 polymorphisms with depression risk

rs2253206

n = 300

n = 479

Codominant

GG

140 (46.7%)

201 (42.0%)

1.00 (Ref)

GA

140 (46.7%)

221 (46.1%)

1.08 (0.79–1.46)

0.64

AA

20 (6.7%)

57 (11.9%)

2.00 (1.15–3.49)

0.01

Dominant

G/G

140 (46.7%)

201 (42.0%)

1.00 (Ref)

GA/AA

160 (53.3%)

278 (58.0%)

1.20 (0.89–1.60)

0.23

Recessive

GG/GA

280 (93.3%)

422 (88.1%)

1.00 (Ref)

AA

20 (6.7%)

57 (11.9%)

1.93 (1.13–3.29)

0.01

Allele

G

420 (70.0%)

623 (65.0%)

1.00 (Ref)

A

180 (30.0%)

335 (35.0%)

1.25 (1.00–1.56)

0.05

rs10932201

n = 301

n = 480

Codominant

AA

158 (52.5%)

178 (37.1%)

1.00 (Ref)

GA

112 (37.2%)

252 (52.5%)

1.81 (1.27–2.58)

0.001

GG

31 (10.3%)

50 (10.4%)

1.02 (0.55–1.90)

0.94

Dominant

AA

158 (52.5%)

178 (37.1%)

1.00 (Ref)

GA/GG

143 (47.5%)

302 (62.9%)

0.74 (0.52–1.04)

0.002

Recessive

AA/GA

270 (89.7%)

430 (89.6%)

1.00 (Ref)

GG

31 (10.3%)

50 (10.4%)

0.87 (0.50–1.51)

0.63

Allele

A

428 (71.1%)

608 (63.3%)

1.00 (Ref)

G

174 (28.9%)

352 (36.7%)

1.29 (1.01–1.65)

0.04

rs162209

n = 329

n = 480

Codominant

AA

206 (62.6%)

321 (66.9%)

1.00 (Ref)

AG

109 (33.1%)

136 (28.3%)

0.72 (0.50–1.03)

0.07

GG

14 (4.3%)

23 (4.8%)

0.86 (0.38–1.98)

0.73

Dominant

AA

206 (62.6%)

321 (66.9%)

1.00 (Ref)

0.08

GA/GG

123 (37.4%)

159 (33.1%)

0.74 (0.52–1.04)

Recessive

AA/GA

315 (95.7%)

457 (95.2%)

1.00 (Ref)

0.99

GG

14 (4.3%)

23 (4.8%)

1.01 (0.45–2.23)

Allele

A

521 (79.2%)

778 (81.2%)

1.00 (Ref)

G

137 (20.8%)

182 (19.0%)

0.81 (0.61–1.07)

0.15