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Table 4 Haplotype analysis of rs4986893 and rs4244285

From: CYP2C19-rs4986893 confers risk to major depressive disorder and bipolar disorder in the Han Chinese population whereas ABCB1-rs1045642 acts as a protective factor

 

rs4986893

rs4244285

 

Control(n = 464)

MDD(n = 439)

BPD(n = 600)

Haplotype 1

G

G

 

656

569

750

Haplotype 2

G

A

 

248

261

386

Haplotype 3

A

G

 

24

48

64

 

MDD

BPD

 

χ2

P

OR (CI 95%)

χ2

P

OR (95% CI)

Overall

13.137

0.001

––

20.065

< 0.001

––

2 vs. 1

3.359

0.067

1.213 (0.987, 1.492)

10.068

0.002

1.361(1.125, 1.648)

3 vs. 1

11.145

0.001

2.306(1.395, 3.812)

12.549

< 0.001

2.332 (1.442, 3.772)

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BMC Psychiatry

ISSN: 1471-244X

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