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Fig. 3 | BMC Psychiatry

Fig. 3

From: CRHR1 antagonist alleviates LPS-induced depression-like behaviour in mice

Fig. 3

Effects of antalarmin on depression-like behaviour induced by LPS administration. A Representative graphs of trajectories during the open field test (OFT). B-C Histograms showing the total travelled distance and the time spent in the central area in the open field test (OFT). D Histogram showing the feeding latencies after fasting in the novelty-suppressed feeding test (NSFT). E-F Histogram showing the immobility time of the mice in the forced swimming test (FST) and the tail suspension test (TST). Data are presented as the mean ± SEM (n = 15 mice in the CON and LPS groups; n = 14 mice in the ANT and LPS-ANT groups). *P < 0.05 and **P < 0.01 vs. CON group; #P < 0.05 and ##P < 0.01 vs. LPS group

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