Relationship between depressive disorders and biochemical indicators in adult men and women

Li, Xinyuan; Mao, Yafei; Zhu, Shumin; Ma, Jin; Gao, Shichao; Jin, Xiuyu; Wei, Zishuan; Geng, Yulan

doi:10.1186/s12888-023-04536-y

BMC Psychiatry

Table 4 Relationship between depressive disorders and biochemical indicators in men

From: Relationship between depressive disorders and biochemical indicators in adult men and women

Variable			Crude model		Model 1		Model 2
Variable	Crude OR (95% CI)	P	Adjusted OR (95% CI)^a	P^a	Adjusted OR (95% CI)^b	P^b	Adjusted OR (95% CI)^c	P^c
Albumin (g/L)	0.94 (0.92 ~ 0.96)	< 0.001	0.95 (0.93 ~ 0.97)	< 0.001	0.95 (0.93 ~ 0.98)	0.001	0.96 (0.93 ~ 0.99)	0.013
Alanineamino transferase (U/L)	1 (1 ~ 1)	0.112	1 (1 ~ 1)	0.044	1 (1 ~ 1.01)	0.033	1 (1 ~ 1.01)	0.166
Aspartate aminotransferase (U/L)	1 (1 ~ 1.01)	0.002	1 (1 ~ 1.01)	0.003	1 (1 ~ 1.01)	0.272	1 (1 ~ 1.01)	0.285
Alkaline phosphatase (U/L)	1 (1 ~ 1)	0.111	1 (1 ~ 1)	0.087	1 (1 ~ 1.01)	0.161	1 (1 ~ 1.01)	0.228
Blood urea nitrogen (mmol/L)	1 (0.97 ~ 1.03)	0.851	0.97 (0.94 ~ 1.01)	0.129	1 (1 ~ 1)	0.087	0.96 (0.91 ~ 1.01)	0.124
Total calcium (mmol/L)	0.72 (0.34 ~ 1.52)	0.388	0.88 (0.41 ~ 1.91)	0.75	0.96 (0.91 ~ 1.01)	0.24	0.73 (0.25 ~ 2.14)	0.566
Cholesterol (mmol/L)	1.04 (0.98 ~ 1.11)	0.154	1.05 (0.99 ~ 1.11)	0.119	0.53 (0.19 ~ 1.52)	0.408	1.02 (0.94 ~ 1.1)	0.65
Bicarbonate (mmol/L)	0.97 (0.94 ~ 1)	0.049	0.97 (0.94 ~ 1)	0.043	1.03 (0.96 ~ 1.12)	0.482	0.99 (0.95 ~ 1.03)	0.747
Creatinine (umol/L)	1 (1 ~ 1)	0.011	1 (1 ~ 1)	0.082	0.99 (0.95 ~ 1.03)	0.457	1 (1 ~ 1)	0.267
Gamma-glutamyl transferase (U/L)	1 (1 ~ 1)	< 0.001	1 (1 ~ 1)	< 0.001	1 (1 ~ 1)	0.013	1 (1 ~ 1)	0.016
Glucose (mmol/L)	1.06 (1.04 ~ 1.09)	< 0.001	1.06 (1.03 ~ 1.08)	< 0.001	1.06 (1.02 ~ 1.09)	0.002	1.05 (1.01 ~ 1.08)	0.012
Iron (umol/L)	0.99 (0.98 ~ 1)	0.02	0.99 (0.98 ~ 1)	0.071	0.99 (0.97 ~ 1)	0.083	0.99 (0.98 ~ 1.01)	0.29
Lactate dehydrogenase (U/L)	1 (1 ~ 1)	0.059	1 (1 ~ 1)	0.135	1 (1 ~ 1)	0.19	1 (1 ~ 1)	0.538
Phosphorus (mmol/L)	0.89 (0.63 ~ 1.25)	0.498	1 (0.7 ~ 1.42)	0.992	1.17 (0.74 ~ 1.86)	0.496	1.28 (0.8 ~ 2.06)	0.298
Total bilirubin (umol/L)	0.97 (0.96 ~ 0.98)	< 0.001	0.97 (0.96 ~ 0.98)	< 0.001	0.97 (0.95 ~ 0.99)	< 0.001	0.97 (0.95 ~ 0.99)	0.001
Total protein (g/L)	0.99 (0.98 ~ 1.01)	0.359	1 (0.98 ~ 1.01)	0.888	0.99 (0.97 ~ 1.01)	0.359	0.99 (0.97 ~ 1.01)	0.39
Triglycerides (mmol/L)	1.06 (1.02 ~ 1.09)	0.001	1.06 (1.02 ~ 1.1)	0.001	1.08 (1.03 ~ 1.12)	0.001	1.06 (1.01 ~ 1.11)	0.01
Uric acid (umol/L)	1 (1 ~ 1)	0.694	1 (1 ~ 1)	0.73	1 (1 ~ 1)	0.479	1 (1 ~ 1)	0.055
Sodium (mmol/L)	0.98 (0.95 ~ 1.01)	0.167	0.98 (0.96 ~ 1.01)	0.193	1.01 (0.97 ~ 1.05)	0.661	1.01 (0.97 ~ 1.05)	0.641
Potassium (mmol/L)	1.28 (1.07 ~ 1.55)	0.008	1.21 (1 ~ 1.46)	0.052	1.17 (0.9 ~ 1.51)	0.243	1.2 (0.92 ~ 1.56)	0.185
Chloride (mmol/L)	0.98 (0.95 ~ 1)	0.02	0.98 (0.95 ~ 1)	0.019	1 (0.97 ~ 1.03)	0.849	1 (0.97 ~ 1.03)	0.763
Osmolality (mmol/Kg)	1.01 (1 ~ 1.02)	0.166	1 (0.99 ~ 1.02)	0.587	1.01 (1 ~ 1.03)	0.158	1.01 (0.99 ~ 1.03)	0.201
Globulin (g/L)	1.03 (1.01 ~ 1.04)	< 0.001	1.03 (1.01 ~ 1.04)	< 0.001	1.01 (0.99 ~ 1.03)	0.168	1.01 (0.99 ~ 1.03)	0.462

Note: SE standard error, OR odds ratio, CI confidence interval
^aAdjusted for age, race
^bAdjusted for age, race, education, ratio of family income to poverty, marital status, whether to drink too much alcohol
^cAdjusted for age, race, education, ratio of family income to poverty, marital status, whether to drink too much alcohol, body mass index, waist circumference

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