Relationship between depressive disorders and biochemical indicators in adult men and women

Li, Xinyuan; Mao, Yafei; Zhu, Shumin; Ma, Jin; Gao, Shichao; Jin, Xiuyu; Wei, Zishuan; Geng, Yulan

doi:10.1186/s12888-023-04536-y

BMC Psychiatry

Table 5 Relationship between depressive disorders and biochemical indicators in women

From: Relationship between depressive disorders and biochemical indicators in adult men and women

Variable			Crude model		Model 1		Model 2
Variable	Crude OR (95% CI)	P	Adjusted OR (95% CI)^a	P^a	Adjusted OR (95% CI)^b	P^b	Adjusted OR (95% CI)^c	P^c
Albumin (g/L)	1.01 (1 ~ 1.01)	0.001	1.01 (1 ~ 1.01)	0.001	0.98 (0.94 ~ 1.02)	0.33	1 (0.95 ~ 1.04)	0.834
Alanineamino transferase (U/L)	1.01 (1 ~ 1.01)	0.001	1 (1 ~ 1.01)	0.002	1.01 (1 ~ 1.01)	0.15	1.01 (1 ~ 1.01)	0.213
Aspartate aminotransferase (U/L)	1.01 (1 ~ 1.01)	0.001	1.01 (1 ~ 1.01)	0.001	1.01 (1 ~ 1.02)	0.074	1.01 (1 ~ 1.02)	0.057
Alkaline phosphatase (U/L)	1.01 (1 ~ 1.01)	< 0.001	1.01 (1 ~ 1.01)	< 0.001	1.01 (1 ~ 1.01)	0.02	1.01 (1 ~ 1.01)	0.032
Blood urea nitrogen (mmol/L)	0.99 (0.97 ~ 1.02)	0.515	0.98 (0.95 ~ 1.01)	0.122	0.99 (0.92 ~ 1.06)	0.703	0.99 (0.92 ~ 1.07)	0.807
Total calcium (mmol/L)	0.81 (0.46 ~ 1.44)	0.48	0.78 (0.44 ~ 1.38)	0.392	0.58 (0.13 ~ 2.53)	0.467	0.68 (0.15 ~ 3.14)	0.622
Cholesterol (mmol/L)	1.04 (0.99 ~ 1.09)	0.128	1.04 (0.98 ~ 1.09)	0.185	1.06 (0.93 ~ 1.21)	0.397	1.07 (0.94 ~ 1.23)	0.317
Bicarbonate (mmol/L)	0.99 (0.97 ~ 1.02)	0.508	0.99 (0.96 ~ 1.01)	0.218	1.05 (0.99 ~ 1.11)	0.092	1.06 (1 ~ 1.13)	0.042
Creatinine (umol/L)	1 (1 ~ 1)	< 0.001	1 (1 ~ 1)	< 0.001	1 (0.99 ~ 1.01)	0.937	1 (1 ~ 1.01)	0.756
Gamma-glutamyl transferase (U/L)	1 (1 ~ 1.01)	< 0.001	1 (1 ~ 1)	< 0.001	1 (1 ~ 1.01)	0.217	1 (1 ~ 1.01)	0.443
Glucose (mmol/L)	1.07 (1.04 ~ 1.09)	< 0.001	1.06 (1.04 ~ 1.09)	< 0.001	0.96 (0.89 ~ 1.04)	0.36	0.94 (0.87 ~ 1.03)	0.182
Iron (umol/L)	0.99 (0.98 ~ 1)	0.019	0.99 (0.98 ~ 1)	0.046	0.99 (0.97 ~ 1.01)	0.496	0.99 (0.97 ~ 1.02)	0.659
Lactate dehydrogenase (U/L)	1 (1 ~ 1)	0.003	1 (1 ~ 1)	0.01	1 (1 ~ 1.01)	0.239	1 (1 ~ 1.01)	0.287
Phosphorus (mmol/L)	1.18 (0.87 ~ 1.59)	0.29	1.22 (0.9 ~ 1.64)	0.206	1.69 (0.77 ~ 3.7)	0.188	1.82 (0.82 ~ 4.06)	0.141
Total bilirubin (umol/L)	0.99 (0.97 ~ 1)	0.021	0.99 (0.97 ~ 1)	0.024	0.99 (0.95 ~ 1.03)	0.533	1 (0.96 ~ 1.03)	0.887
Total protein (g/L)	1 (0.99 ~ 1.01)	0.934	1 (0.99 ~ 1.01)	0.934	0.98 (0.95 ~ 1.01)	0.195	0.99 (0.95 ~ 1.02)	0.374
Triglycerides (mmol/L)	1.14 (1.09 ~ 1.19)	< 0.001	1.14 (1.09 ~ 1.2)	< 0.001	1.11 (0.97 ~ 1.28)	0.135	1.07 (0.92 ~ 1.25)	0.358
Uric acid (umol/L)	1 (1 ~ 1)	0.037	1 (1 ~ 1)	0.053	1 (1 ~ 1)	0.639	1 (1 ~ 1)	0.286
Sodium (mmol/L)	1 (0.98 ~ 1.03)	0.73	1 (0.98 ~ 1.02)	0.958	1.07 (1.01 ~ 1.12)	0.02	1.08 (1.02 ~ 1.14)	0.01
Potassium (mmol/L)	1.04 (0.9 ~ 1.22)	0.575	1.03 (0.88 ~ 1.2)	0.734	1.42 (0.95 ~ 2.1)	0.084	1.36 (0.9 ~ 2.04)	0.141
Chloride (mmol/L)	0.99 (0.97 ~ 1)	0.163	0.99 (0.97 ~ 1)	0.154	1.02 (0.98 ~ 1.07)	0.307	1.03 (0.98 ~ 1.09)	0.183
Osmolality (mmol/Kg)	1.01 (1 ~ 1.02)	0.01	1.01 (1 ~ 1.02)	0.051	1.02 (1 ~ 1.05)	0.094	1.03 (1 ~ 1.05)	0.072
Globulin (g/L)	1.02 (1.01 ~ 1.03)	0.002	1.02 (1.01 ~ 1.03)	0.005	0.99 (0.96 ~ 1.02)	0.549	0.99 (0.95 ~ 1.02)	0.428

Note: SE standard error, OR odds ratio, CI confidence interval
^aAdjusted for age, race
^bAdjusted for age, race, education, ratio of family income to poverty, marital status, alcohol intake status, whether to drink too much alcohol
^cAdjusted for age, race, education, ratio of family income to poverty, marital status, alcohol intake status, whether to drink too much alcohol, body mass index, waist circumference

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