From: The impact of antipsychotic adherence on acute care utilization
0 – 6 Months | 6 -12 Months | |||
---|---|---|---|---|
OR (95% CI) | P-value | OR (95% CI) | P-value | |
Cohort | ||||
Psychiatric Control (reference) | 1.00 | 1.00 | ||
Bipolar Disorder | 0.66 (0.50, 0.88) | 0.004 | 0.96 (0.71, 1.30) | 0.788 |
Schizophrenia | 0.74 (0.55, 1.00) | 0.050 | 0.95 (0.68, 1.33) | 0.766 |
Age | 1.01 (1.00, 1.02) | 0.228 | 1.00 (0.99, 1.01) | 0.463 |
Female | 0.86 (0.68, 1.08) | 0.199 | 0.96 (0.75, 1.24) | 0.762 |
Medicaid | 0.81 (0.59, 1.10) | 0.170 | 0.64 (0.46, 0.90) | 0.010 |
Medicare | 1.16 (0.81, 1.67) | 0.413 | 1.10 (0.75, 1.62) | 0.614 |
Diabetes | 1.25 (0.97, 1.62) | 0.087 | 1.23 (0.94, 1.62) | 0.133 |
CHF | 1.77 (1.17, 2.69) | 0.007 | 2.33 (1.54, 3.53) | < 0.001 |
OSA | 0.93 (0.60, 1.45) | 0.760 | 2.07 (1.34, 3.19) | 0.001 |
Hypertension | 0.94 (0.72, 1.21) | 0.620 | 0.99 (0.75, 1.31) | 0.927 |
MI | 1.68 (0.71, 3.96) | 0.236 | 0.57 (0.23, 1.41) | 0.220 |
Cerebrovascular Disease | 1.33 (0.83, 2.16) | 0.241 | 1.57 (0.97, 2.54) | 0.069 |
COPD | 1.24 (0.91, 1.70) | 0.167 | 1.44 (1.05, 1.98) | 0.024 |
Depression | 0.90 (0.71, 1.14) | 0.372 | 1.05 (0.81, 1.35) | 0.722 |
Cancer | 1.34 (0.89, 2.02) | 0.168 | 1.96 (1.28, 2.98) | 0.002 |
Anxiety | 0.99 (0.78, 1.26) | 0.924 | 1.13 (0.87, 1.46) | 0.356 |
Dementia | 1.02 (0.59, 1.77) | 0.943 | 0.61 (0.34, 1.09) | 0.094 |
Alcohol Abuse | 1.15 (0.82, 1.63) | 0.415 | 1.45 (1.02, 2.07) | 0.041 |
Substance Abuse | 1.13 (0.88, 1.45) | 0.347 | 1.09 (0.83, 1.43) | 0.545 |
Adherence/Switch Categories | ||||
No Switch & Adherence 0.8 + (reference) | 1.00 | 1.00 | ||
No Switch & Adherence < 0.5 | 1.34 (0.87, 2.06) | 0.189 | 1.58 (1.02, 2.46) | 0.042 |
No Switch & Adherence 0.5 – 0.79 | 1.52 (1.12, 2.07) | 0.007 | 1.59 (1.15, 2.20) | 0.005 |
Switch & Adherence < 0.5 | 2.85 (1.33, 6.15) | 0.007 | 1.29 (0.52, 3.16) | 0.581 |
Switch & Adherence 0.5—0.79 | 2.49 (1.56, 3.98) | < 0.001 | 1.04 (0.60, 1.81) | 0.885 |
Switch & Adherence ≥ 0.8 | 2.13 (1.41, 3.22) | < 0.001 | 1.06 (0.66, 1.72) | 0.805 |
Stop | 1.70 (1.24, 2.33) | 0.001 | 1.23 (0.88, 1.73) | 0.233 |
Any Inpatient Stay Prior Year | 4.27 (3.35, 5.44) | < 0.001 | 2.86 (2.19, 3.74) | < 0.001 |
Any ED Visit Prior Year | 1.96 (1.53, 2.51) | < 0.001 | 1.69 (1.28, 2.22) | < 0.001 |
7% Weight Gain | 0.99 (0.75, 1.30) | 0.917 | 1.19 (0.89, 1.61) | 0.245 |