Table 3 Comparison of genotype frequencies of HTR3B gene polymorphism loci between case and control groups
SNP(A1/A2) | Group | genotype(%) | χ2 | P | ||
|---|---|---|---|---|---|---|
A1A1 | A1A2 | A2A2 | ||||
rs10789970 (C/T) | case (227) | 39(17.2) | 113(49.8) | 75(33.0) | 0.766 | 0.682 |
control (200) | 32(16.0) | 108(54.0) | 60(30.0) | |||
rs4938056 (C/T) | case (229) | 43(18.8) | 113(49.3) | 73(31.9) | 1.123 | 0.570 |
control (202) | 34(16.8) | 110(54.5) | 58(28.7) | |||
rs12421126 (C/T) | case (201) | 8(4.0) | 67(33.3) | 126(62.7) | 2.278 | 0.320 |
control (176) | 4(2.3) | 70(39.8) | 102(58.0) | |||
rs1176744 (A/C) | case (227) | 141(62.1) | 81(35.7) | 5(2.2) | 11.129 | 0.004* |
control (200) | 100(50.0) | 84(42.0) | 16(8.0) | |||
rs12795805 (C/T) | case (227) | 6(2.6) | 73(32.2) | 148(65.2) | 4.852 | 0.088 |
control (200) | 4(2.0) | 46(23.0) | 150(75.0) | |||