Table 8 Comparison of the correlations between genotype and allele carriers and cognitive function at different loci
SNP(A1/A2) | rs1176744(A/C) | rs10789970 (C/T) | rs4938056(C/T) | ||||||
|---|---|---|---|---|---|---|---|---|---|
LT | SSIOT | EMT | LT | SSIOT | EMT | LT | SSIOT | EMT | |
A1A1 | 46.922±23.457 | 4.577±0.148 | 7.768±1.753 | 46.744±21.631 | 4.937±0.306 | 8.059±1.520 | 46.256±21.139 | 4.820±0.290 | 8.031±1.459 |
A1A2 | 47.321±21.661 | 6.004±0.196 | 8.184±1.516 | 48.434±25.133 | 5.037±0.179 | 7.886±1.646 | 48.726±25.331 | 5.144±0.178 | 7.906±1.661 |
A2A2 | 48.800±6.140 | 7.438±0.784 | 8.244±0.147 | 45.293±18.660 | 5.428±0.220 | 7.922±1.769 | 45.178±18.248 | 5.346±0.222 | 7.888±1.770 |
A1A1+A1A2 | 47.068±22.770 | 5.098±0.126 | 7.920±1.678 | 48.000±24.224 | 5.004±1.886 | 7.930±1.611 | 48.045±24.207 | 5.048±1.907 | 7.941±1.604 |
A2A2+A1A2 | 47.407±21.059 | 6.126±1.930 | 8.187±1.471 | 47.181±22.770 | 5.207±1.937 | 7.900±1.691 | 46.652±22.939 | 5.236±1.980 | 7.835±1.676 |
F | 0.022 | 21.134 | 1.709 | 0.442 | 1.238 | 0.157 | 0.590 | 1.038 | 0.110 |
t1 | -0.170 | -5.478 | -0.430 | 0.851 | -1.627 | 0.037 | 0.899 | -1.148 | 0.221 |
t2 | 0.157 | 6.262 | 1.851 | 0.110 | 0.987 | -0.543 | -0.710 | 1.540 | -1.815 |
P | 0.978 | 0.000 | 0.183 | 0.644 | 0.292 | 0.855 | 0.555 | 0.356 | 0.896 |
P1 | 0.899 | 0.000 | 0.086 | 0.687 | 0.778 | 0.574 | 0.541 | 0.342 | 0.691 |
P2 | 0.855 | 0.000 | 0.523 | 0.745 | 0.195 | 0.673 | 0.804 | 0.151 | 0.653 |
P3 | 0.887 | 0.078 | 0.915 | 0.352 | 0.170 | 0.890 | 0.295 | 0.479 | 0.919 |
P4 | 0.865 | 0.003 | 0.667 | 0.396 | 0.105 | 0.971 | 0.370 | 0.252 | 0.826 |
P5 | 0.875 | 0.000 | 0.065 | 0.912 | 0.325 | 0.588 | 0.478 | 0.125 | 0.071 |
SNP(A1/A2) | rs12421126(C/T) | rs12795805(C/T) | ||||
|---|---|---|---|---|---|---|
LT | SSIOT | EMT | LT | SSIOT | EMT | |
A1A1 | 41.750±14.210 | 4.124±0.648 | 8.734±1.888 | 49.167±18.115 | 6.320±0.764 | 8.005±0.518 |
A1A2 | 44.910±23.469 | 4.805±0.223 | 7.895±1.777 | 46.699±21.838 | 5.612±0.219 | 8.021±1.706 |
A2A2 | 48.984±23.368 | 5.221±0.163 | 7.961±1.631 | 47.223±23.142 | 4.873±0.154 | 7.878±1.673 |
A1A1+A1A2 | 44.516±23.368 | 4.972±2.093 | 7.918±1.744 | 46.886±21.486 | 5.682±1.732 | 8.020±1.644 |
A2A2+A1A2 | 47.230±22.767 | 5.174±1.929 | 7.900±1.656 | 47.050±22.671 | 5.117±1.923 | 7.925±1.681 |
F | 0.921 | 2.157 | 0.884 | 0.039 | 5.006 | 0.188 |
t1 | -1.486 | -1.170 | -0.050 | -0.107 | 3.223 | 0.614 |
t2 | 0.482 | 0.892 | -0.962 | -0.227 | -1.530 | -0.116 |
P | 0.400 | 0.118 | 0.415 | 0.962 | 0.007 | 0.873 |
P1 | 0.715 | 0.321 | 0.190 | 0.798 | 0.374 | 0.947 |
P2 | 0.392 | 0.102 | 0.211 | 0.837 | 0.065 | 0.812 |
P3 | 0.246 | 0.134 | 0.818 | 0.871 | 0.006 | 0.624 |
P4 | 0.139 | 0.243 | 0.960 | 0.915 | 0.002 | 0.549 |
P5 | 0.631 | 0.373 | 0.337 | 0.821 | 0.127 | 0.908 |