Skip to main content

Table 1 Descriptive statistics of schizophrenia patients and healthy controls

From: Study on correlations of BDNF, PI3K, AKT and CREB levels with depressive emotion and impulsive behaviors in drug-naïve patients with first-episode schizophrenia

 

Patients

Controls

t/Z/χ²

P

 

(n = 70)

(n = 69)

  

Gender(male/female, n)a

43/27

35/34

1.617

0.234

Marital status(single/married, n)a

57/13

22/47

34.768

0.000

smoking(yes/no, n) a

29/41

19/50

2.966

0.109

Age(year)b

25.00 ± 14.30

32.00 ± 12.50

-3.738

0.000

Education (years)b

12.00 ± 7.00

12.00 ± 5.50

-0.729

0.466

BMI(kg/m²)b

21.48 ± 3.52

20.96 ± 3.22

-0.613

0.540

Total PANSS scoreb

87.46 ± 5.77

54.00 ± 9.00

-10.180

0.000

Total CDSS scoreb

6.00 ± 8.00

1.00 ± 2.00

-7.234

0.000

Total S-UPPS-P scorec

48.19 ± 8.41

37.07 ± 6.47

-8.724

0.000

 S-UPPS-P

    

 NU subscore b

11.00 ± 3.30

7.00 ± 4.00

-5.442

0.000

 PU subscore b

10.00 ± 4.30

9.00 ± 4.00

-2.820

0.005

 SS subscore b

10.00 ± 4.00

8.00 ± 4.00

-4.161

0.000

 PR subscore b

8.27 ± 2.76

6.00 ± 2.00

-5.482

0.000

 PE subscore b

8.97 ± 2.71

6.00 ± 2.50

-6.202

0.000

Levels of protein factor(x¯±s)

   

 BDNF(ng/mL) b

3.64 ± 1.60

5.27 ± 1.51

-7.149

0.000

 PI3K(ng/mL)c

3.95 ± 1.38

5.49 ± 2.07

5.146

0.000

 AKT(umol/L)

10.79 ± 2.28 c

8.14 ± 2.44 b

-6.102

0.000

 CREB(ng/mL) b

1.95 ± 1.13

2.76 ± 1.38

-5.228

0.000

  1. BMI, body mass index; PANSS, Positive and Negative Syndrome Scale; CDSS, Calgary Depression Scale for Schizophrenia; S-UPPS-P, The Short UPPS-P Impulsive Behavior Scale; NU, Negative urgency; PU, positive urgency; SS, sensation seeking; PR, lack of premeditation; PE, and lack of perseveration; BDNF, brain-derived neurotrophic factor; PI3K, phosphoinositide-3-kinase; AKT, protein kinase B; CREB, cyclic AMP response-element binding protein. The data were expressed as the number of cases or the average standard deviation or the median quartile interval. a, chi-square test; b, nonparametric test; c, t test.