The effect of cognitive behavioral therapy on depression and anxiety of women with polycystic ovary syndrome: a randomized controlled trial

Table 2 Comparison of the mean score of depression and anxiety among study groups

Variable	CBT^* (n = 42) Mean (SD^†)	Control (n = 42) Mean (SD^†)	Mean Difference (95% Confidence Interval)	P-value
Depression (Score range: 0 to 63)
Before intervention	24.4 (5.0)	23.3 (3.2)	-1.0 (2.9 to 0.7)	0.25^‡
After intervention	6.7 (4.3)	24.5 (2.8)	-18.6 (-19.4 to -17.8)	< 0.001^§
State anxiety (Score range: 20 to 80)
Before intervention	42.9 (2.9)	42.2 (2.9)	0.7 (-2.0 to 0.5)	0.27^‡
After intervention	29.0 (3.9)	42.3 (2.8)	-15.3 (-16.2 to -14.3)	< 0.001^§
Trait anxiety (Score range: 20 to 80)
Before intervention	41.8 (2.8)	41.1 (2.9)	0.7 (-1.9 to 0.5)	0.25^‡
After intervention	29.3 (4.3)	41.3 (2.9)	-15.0 (-16.0 to -13.9)	< 0.001^§

^* Cognitive Behavioral Therapy; ^† Standard Deviation; ^‡Independent t-test; ^§ ANCOVA with adjusting the baseline value and the variables of couples occupation, stress role, and infertility evaluation

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