Table 1 Baseline characteristics of participants
Characteristics | Unexposed group | Exposed group |
|---|---|---|
Total cohort | 691 449 | 345 903 |
Number of deaths | 32 288 (4·7) | 18 962 (5·5) |
Follow-up, median (IQR) years | 4·3 (1·7–8·1) | 4·5 (1·9 − 8·4) |
Age, median (IQR) years | 43·0 (31·5–56·4) | 43·0 (31·5–56·4) |
Male | 245 919 (35·6) | 122 980 (35·6) |
Ethnic group | ||
Black | 7 570 (1·1) | 2 218 (0·6) |
Mixed race | 2 018 (0·3) | 979 (0·3) |
White | 247 556 (35·8) | 137 640 (39·6) |
Other | 5 107 (0·7) | 1 381 (0·4) |
South Asian | 11 884 (1·7) | 4 087 (1·2) |
Missing | 417 314 (60·4) | 200 154 (57·9) |
Townsend deprivation quintile | ||
1 (least deprived) | 154 245 (22·3) | 69 425 (20·1) |
2 | 130 804 (18·9) | 61 111 (17·7) |
3 | 126 405 (18·3) | 63 231 (18·3) |
4 | 110 137 (15·9) | 59 887 (17·3) |
5 (most deprived) | 80 121 (11·6) | 47 240 (13·7) |
Missing | 89 737 (13·0) | 45 009 (13·0) |
Current smoker | 141 762 (20·5) | 98 779 (28·6) |
Alcohol use | ||
Non-drinker | 107 507 (15·6) | 57 456 (16·6) |
Light-moderate drinker | 420 498 (60·8) | 210 698 (60·9) |
Heavy drinker | 19 434 (2·8) | 23 458 (6·8) |
Missing | 144 010 (20·8) | 54 291 (15·7) |
Comorbid depression | 72 824 (10·5) | 171 294 (49·5) |
Comorbid SMI | 5 139 (0·7) | 6 796 (2·0) |
Charlson comorbidity index | ||
0 (no comorbidities) | 518 737 (75·0) | 239 378 (69·2) |
1 | 123 192 (17·8) | 75 709 (21·9) |
2 | 32 699 (4·7) | 19 605 (5·7) |
3 | 10 582 (1·5) | 6 990 (2·0) |
4 | 3 428 (0·5) | 2 222 (0·6) |
≥5 | 2 811 (0·4) | 1 999 (0·6) |