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Table 1 Characteristics of participants by depressive status, NHANES (2011–2016). Weighted

From: Association between serum copper, zinc, and selenium concentrations and depressive symptoms in the US adult population, NHANES (2011–2016)

 

n (%)

Non-depressive group

(PHQ-9 < 10, %)

Depressive group

(PHQ-9 ≥ 10, %)

P value

All participants

4552 (100.00)

4159 (91.37)

393 (8.63)

——

Gender

   

0.001

 Male

2311 (50.77)

2152 (93.12)

159 (6.88)

 

 Female

2241 (49.23)

2007 (89.56)

234 (10.44)

 

Age, years

   

< 0.001 ***

 20–45

1986 (43.63)

1853 (93.30)

133 (6.70)

 

 46–69

1841 (40.44)

1642 (89.19)

217 (11.79)

 

 > 69

725 (15.93)

682 (94.07)

43 (5.93)

 

Age, years (SD)

48.22 (17.03)

48.21 (17.14)

48.32 (15.72)

0.918

Race

   

0.028 *

 Mexican American

617 (13.55)

572 (92.71)

45 (7.29)

 

 Other Hispanic

491 (10.79)

433 (88.19)

58 (11.81)

 

 Non-Hispanic White

1812 (39.81)

1651 (91.11)

161 (8.89)

 

 Non-Hispanic Black

971 (21.33)

882 (90.83)

89 (9.17)

 

 Other Race

661 (14.52)

621 (93.95)

40 (6.05)

 

Educational level, years

   

< 0.001 ***

 < 9

438 (9.62)

377 (86.07)

61 (13.93)

 

 9–11

575 (12.68)

491 (85.39)

84 (14.61)

 

 12

987 (21.68)

896 (90.78)

91 (9.22)

 

 > 12

2552 (56.06)

2395 (93.85)

157 (6.15)

 

Marital status

   

< 0.001 ***

 Married

2275 (49.98)

2141 (94.11)

134 (5.89)

 

 Widowed

335 (7.36)

298 (88.96)

37 (11.04)

 

 Divorced

496 (10.90)

421 (84.88)

75 (15.12)

 

 Separated

134 (2.94)

110 (82.09)

24 (17.91)

 

 Unmarried

927 (20.36)

842 (90.83)

85 (9.17)

 

 Cohabitation

385 (8.46)

347 (90.13)

38 (9.87)

 

Family size

   

0.125

 1

1071 (23.53)

950 (88.70)

121 (11.30)

 

 2–4

2536 (55.71)

2340 (92.27)

196 (7.73)

 

 > 4

945 (20.76)

869 (91.96)

76 (8.04)

 

Family income ($)

   

< 0.001 ***

 < 15,000

732 (16.08)

602 (82.24)

130 (17.76)

 

 15,000–44,999

1823 (40.05)

1639 (89.91)

184 (10.09)

 

 45,000–99,999

1247 (27.39)

1186 (95.11)

61 (4.89)

 

 ≥ 100,000

750 (16.48)

732 (97.60)

18 (2.40)

 

Body mass index (BMI)

   

0.029 *

 < 25 kg/m2

1321 (29.02)

1232 (93.26)

89 (6.74)

 

 25 to < 30 kg/m2

1476 (32.43)

1373 (93.02)

103 (6.98)

 

 ≥ 30 kg/m2

1755 (38.55)

1554 (88.55)

201 (11.45)

 

Smoking

   

< 0.001 ***

 Yes

1994 (43.80)

1749 (87.71)

245 (12.29)

 

 No

2558 (56.20)

2410 (94.21)

148 (5.79)

 

Alcohol drinking

   

< 0.001 ***

 Yes

695 (15.27)

574 (82.59)

121 (17.41)

 

 No

3857 (84.73)

3589 (93.05)

268 (6.95)

 

Diabetes

   

< 0.001 ***

 Yes

763 (16.76)

654 (85.71)

109 (14.29)

 

 No

3789 (83.24)

3505 (92.50)

284 (7.50)

 

Hypertension

   

< 0.001 ***

 Yes

1678 (36.86)

1472 (87.72)

206 (12.28)

 

 No

2874 (63.14)

2687 (93.49)

187 (6.51)

 

Trace element (SD)

    

 Copper (Cu, µg/dL)

117.50 (28.85)

116.99 (29.00)

123.88 (26.05)

< 0.001 ***

 Selenium (Se, µg/L)

130.41 (18.65)

130.55 (18.64)

128.75 (18.71)

0.122

 Zinc (Zn, µg/dL)

82.21 (15.23)

82.32 (15.35)

80.85 (13.60)

0.158

  1. *p < 0.05, **p < 0.01, ***p < 0.001
  2. Abbreviations: SD: Standard deviation; n, sample size; NHANES, National Health and Nutrition Examination Survey; PHQ-9, the Patient Health Questionnaire-9 Items