Table 2 Weighted odds ratios (95% confidence intervals) for depressive symptoms across quartiles of copper, zinc, and selenium, NHANES (2011–2016)

Cu (µg/dL)

 Q1 (< 99.20)

ref

ref

ref

 Q2 (99.20–114.55)

1.137 (0.631, 2.046)

1.099 (0.595, 2.033)

0.876 (0.449, 1.711)

 Q3 (114.56–133.60)

2.07 (1.312, 3.264) ^**

1.925 (1.186, 3.124) ^**

1.149 (0.676, 1.955)

 Q4 (>133.60)

2.193 (1.32, 3.645) ^**

1.932 (1.090, 3.424) ^*

1.037 (0.539, 1.993)

 P for trend

< 0.001

0.002

0.716

Se (µg/L)

 Q1 (< 118.40)

ref

ref

ref

 Q2 (118.40–128.40)

0.866 (0.608, 1.232)

0.894 (0.625, 1.281)

1.003 (0.679, 1.483)

 Q3 (128.41–139.80)

0.727 (0.459, 1.151)

0.768 (0.481, 1.226)

0.9 (0.544, 1.489)

 Q4 (>139.80)

0.91 (0.655, 1.265)

1 (0.705, 1.418)

1.201 (0.817, 1.765)

 P for trend

0.548

0.924

0.430

Zn (µg/dL)

 Q1 (< 71.30)

ref

ref

ref

 Q2 (71.30–80.40)

1.577 (1.078, 2.307) ^*

1.593 (1.089, 2.329) ^*

1.566 (1.037, 2.363) ^*

 Q3 (80.41–90.40)

0.961 (0.562, 1.644)

0.992 (0.583, 1.686)

1.012 (0.564, 1.816)

 Q4 (> 90.40)

0.870 (0.581, 1.301)

0.942 (0.623, 1.424)

0.871 (0.555, 1.369)

 P for trend

0.129

0.285

0.221